ID L5K553_PTEAL Unreviewed; 632 AA.
AC L5K553;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=CXXC-type zinc finger protein 1 {ECO:0000256|ARBA:ARBA00023828};
GN ORFNames=PAL_GLEAN10023041 {ECO:0000313|EMBL:ELK05613.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK05613.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KB031041; ELK05613.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K553; -.
DR STRING; 9402.L5K553; -.
DR eggNOG; KOG1632; Eukaryota.
DR InParanoid; L5K553; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd15553; PHD_Cfp1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR022056; CpG-bd_C.
DR InterPro; IPR037869; Spp1/CFP1.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR002857; Znf_CXXC.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46174; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR PANTHER; PTHR46174:SF1; CXXC-TYPE ZINC FINGER PROTEIN 1; 1.
DR Pfam; PF12269; CpG_bind_C; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF02008; zf-CXXC; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51058; ZF_CXXC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00509}.
FT DOMAIN 31..81
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 143..194
FT /note="CXXC-type"
FT /evidence="ECO:0000259|PROSITE:PS51058"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 406..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 89..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..333
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 632 AA; 72455 MW; C9854148CABD56F0 CRC64;
MGGIPQEGDG SDPEPADAGE DSKSENGENA PIYCICRKPD INCFMIGCDN CNEWFHGDCI
RITEKMAKAI REWYCRECQE KDPKLEIRYR HKKSRERDSN ERDGSEPRDE GGGRKRPAPD
PDLQRRAGSG TGVGAILARG SASPHKSSPQ PLGATPSQAC RRTEDCGHCD FCRDMKKFGG
PNKIRQKCRL RQCQLRARLS PVTPSESLPR PRRPLPTQQQ PQPSQKLGRT REDEGAVASS
AVKEPPEATA TPEPLSDEDL PLDPDLYQDF CAGAFDDHGL PWMSDTEESP FLDPALRKRA
VKVKHVKRRE KKSEKKKEER YKRHRQKQKH KDKWKHPERA DVKDPASLPQ CLGPGCVRPA
QPGSKYCSDD CGMKLAANRI YEILPQRIQQ WQQSPCIAEE HGKKLLERIR REQQSARTRL
QEMERRFHEL ESIIARAKQQ AVREDEESNE GDSDDTDLQI FCVSCGHPIN PRVALRHMER
CYAKYESQTS FGSMYPTRIE GATRLFCDVY NPQSKTYCKR LQVLCPEHSR DPKVPADEVC
GCPLVRDVFE LTGDFCRLPK RQCNRHYCWE KLRRAEVDLE RVRVWYKLDE LFEQERNVRT
AMTNRAGLLA LMLHQTIQHD PLTTDLRSSA DR
//
