ID   L5K5G9_PTEAL            Unreviewed;       288 AA.
AC   L5K5G9;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Carbonic anhydrase 14 {ECO:0000313|EMBL:ELK06021.1};
GN   ORFNames=PAL_GLEAN10017532 {ECO:0000313|EMBL:ELK06021.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK06021.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC       {ECO:0000256|ARBA:ARBA00010718}.
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DR   EMBL; KB031037; ELK06021.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5K5G9; -.
DR   STRING; 9402.L5K5G9; -.
DR   eggNOG; KOG0382; Eukaryota.
DR   InParanoid; L5K5G9; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR   PANTHER; PTHR18952:SF84; CARBONIC ANHYDRASE 14; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..288
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003968861"
FT   DOMAIN          21..279
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000259|PROSITE:PS51144"
SQ   SEQUENCE   288 AA;  32430 MW;  6584829734405CD9 CRC64;
     MMFFMLLLEV IWILAADGGQ HHWTYEGPHG QHHWQASYPE CGSHAQSPIN IQTDRVTFDP
     ELPAVQPHGY DQPGLKPLDL HNNGHTVQLS LPPSLYLEGL PRKYVAAQLH LHWGQKGSPG
     GSEHQINSEA TAAELHIVHY DSESYHALSE AAQRPQGLAV LGILIEVGET KNPAYEHILS
     HLHKIRYKGQ NTSVPPFDVG GLLPPLRAQF FRYNGSLTTP PCYQSVLWTV FSRRAQISLE
     QLEKLQETLF SSETDPSELL VQNYRAPQPL NQRPVFASFI QDMDKIFP
//