ID   L5K6Y9_PTEAL            Unreviewed;       699 AA.
AC   L5K6Y9;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=EF-hand domain-containing family member C2 {ECO:0000256|ARBA:ARBA00039880};
GN   ORFNames=PAL_GLEAN10003589 {ECO:0000313|EMBL:ELK07464.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07464.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000256|ARBA:ARBA00035003}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000256|ARBA:ARBA00004430}.
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DR   EMBL; KB030969; ELK07464.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5K6Y9; -.
DR   STRING; 9402.L5K6Y9; -.
DR   eggNOG; KOG0043; Eukaryota.
DR   InParanoid; L5K6Y9; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.29.170; -; 3.
DR   InterPro; IPR006602; DM10_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR   PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12086:SF11; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR   Pfam; PF06565; DM10_dom; 4.
DR   SMART; SM00676; DM10; 3.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS51336; DM10; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          42..149
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
FT   DOMAIN          193..335
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
FT   DOMAIN          399..506
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
SQ   SEQUENCE   699 AA;  81728 MW;  6A744A10EEA6CF49 CRC64;
     MLLSEGKPGI GGEPLLREKT KPKYSVFTKE IGSDVPSWVA FDRQVLSFDA YVEDEVPDKS
     QEKYRIRFYK IFFYLEDDTI QVTEPVVKNS GLRQGTFIQR RRISLPPPDD DQFYTVYHFN
     INIDIVFYGW AFKIYDCDVF TKNFLKKIGI KLNPPGECPE DPYMKTWRQK LDCIRPLRPY
     ESFDTLKQFL EYDRKVLRFF CLWDDSASLF GDRRELILLY FLSDDTIEIK ELLPHNTGRD
     AMPFFLRRRK LPKYGPPGIY QPGAITDRVV LNLYSGLAEN RVYGYLLDKC KLGKLEQEFY
     KDSDLSIGTT INVWGRKVLL CDCDEFTKTY YKTKYGIENF TSIPWKAPSP PKIERKFPPY
     TGFGSEEDSL RSCIGLVPMP RPNLGNFRKF MEKDSYGSIS NILRFFAKLI THKCADVDRL
     FIISYFLSDD TISVFEPIER NSGNAGGQFL KRMRVKKPGQ EVFKSELSEY MKVEELYIGA
     TVNVNGYLFL LLNADEYTLK FMEKNSEKFP FSNLELALQK LKDEKSKSRE IKQVFRDADP
     AFTKMVDYNT FRDIVMTITV GKLIEQELVT IARHYGVPED PCPDTNTLIA MAHEQLKKNF
     FENFERLIYS CVYQDREKKK VLPSKDIKRL CKSSRLPLTD DLLGSLLSKV YDSTDRQLHF
     VTIDEQRCED MWLGMPSPIP TKYINYFQFL KDVYGLEEE
//