ID L5K7C6_PTEAL Unreviewed; 190 AA.
AC L5K7C6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Mitotic spindle assembly checkpoint protein MAD2A {ECO:0000313|EMBL:ELK07619.1};
GN ORFNames=PAL_GLEAN10013916 {ECO:0000313|EMBL:ELK07619.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07619.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the MAD2 family.
CC {ECO:0000256|ARBA:ARBA00010348}.
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DR EMBL; KB030951; ELK07619.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K7C6; -.
DR STRING; 9402.L5K7C6; -.
DR eggNOG; KOG3285; Eukaryota.
DR InParanoid; L5K7C6; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR Gene3D; 3.30.900.10; HORMA domain; 1.
DR InterPro; IPR003511; HORMA_dom.
DR InterPro; IPR036570; HORMA_dom_sf.
DR InterPro; IPR045091; Mad2-like.
DR PANTHER; PTHR11842; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2; 1.
DR PANTHER; PTHR11842:SF11; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A; 1.
DR Pfam; PF02301; HORMA; 1.
DR SUPFAM; SSF56019; The spindle assembly checkpoint protein mad2; 1.
DR PROSITE; PS50815; HORMA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 1..182
FT /note="HORMA"
FT /evidence="ECO:0000259|PROSITE:PS50815"
SQ SEQUENCE 190 AA; 21859 MW; 6B362B0B363E3FC6 CRC64;
MSSWNLHQTA FGINSILYQR GVYPSETFTR VQKYGLTLLV TTDPELMKYL NNVVEQLKDW
LYKCSVQKLV VVISNIESGE VLERWQFDIE CDKTAKDDST PREKSQKAIQ DEIRSVIRQI
TATVTFLPLL EVSCSFDLLI YTDKDLVVPE KWEESGPQFI ANSEQVRLRS FTTTVHKVNS
SVAYKIPVND
//
