ID L5K806_PTEAL Unreviewed; 964 AA.
AC L5K806;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=SH3 and multiple ankyrin repeat domains protein 3 {ECO:0000313|EMBL:ELK07497.1};
GN ORFNames=PAL_GLEAN10004096 {ECO:0000313|EMBL:ELK07497.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07497.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030957; ELK07497.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K806; -.
DR STRING; 9402.L5K806; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG4375; Eukaryota.
DR InParanoid; L5K806; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24135; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN; 1.
DR PANTHER; PTHR24135:SF4; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 89..122
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 157..189
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 190..222
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 328..390
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 431..525
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 315..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..772
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 796..829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 964 AA; 103104 MW; 9DA60F55DF379051 CRC64;
MISSLRNSTR RSPEQVLRVA GGLATDSGYR GCWVHGLVVS SSPMRLLLTP LAGLANLKKF
MDYIQLHSTD KVARLLDKGL DPNFHDPDSG ECPLSLAAQL DGAADLLKTL LDLGASPDYK
DSRGLTPLYH SALGGGDALC CELLLHDHAQ LGTTDENGWQ EIHQACRFGH VQHLEHLLFY
GADMGAQNAS GNTALHVCAL YNQESCARVL LFRGANKDVR NYNSQTAFQV AIVAGNFELA
EVIKTHKDAD VVPFRETPSY AKRRRLAGPS GLASPRPLQR SASDINLKGE VQPAASPGPS
LRSLPHQLLL QRLQEEKDRD RDADQESDVG GLAAGRGGQS KLSPQGEGEI PLHRGEAVKV
LSIGEGGFWE GTVKGRTGWF PADCVEEVQM RQYDTRHETR EDRTKRLFRH YTVGSYDSLT
SHSDYVIDDK VAVLQKRDHE GFGFVLRGAK AETPIEEFTP TPAFPALQYL ESVDVEGVAW
RAGLRTGDFL LEVNGVNVVK VGHKQVVALI RQGGNRLVMK VVSVTRKPEE DGARRRAPPP
PKRAPSTTLT LRSKSMTAEL EELEKLDEIL AAAAEPALRP DIADADSRAA TVRPRPTSRR
ITPAEISSLF ERQGLPGPEK LPGSLRKGIP RTKSVGTQGR GAAGGMQGES HPGGEGTGSS
PHLQLGFPAP TQSAVVAEPL PSPRAQPPGS TPTDSGPGQG SSEEEPELVF AVNLPPAQLS
SSDEETREEL ARIGLVPPPE EFANGVLLAT PLPGPGPSPT TVPGPASGKP SSELPPAPES
AADSGVEEAD TRSSSDPHLE TTSTISTVSS MSTLSSESGE LTDTHTSFAD GHTFLLEKPP
VPPKPKLKSP LGKGPVTFRD PLLKQSSDSE LMAQQHLVAS AGVASAAGPA RPRYLFQRRS
KLWGDPVESR GLPTPEDDKP TVISELSSRL QQLNKDTRSL GEEPVGGLGG LLDPAKKSSI
AAAR
//
