ID L5K8A8_PTEAL Unreviewed; 1164 AA.
AC L5K8A8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Structural maintenance of chromosomes protein 1B {ECO:0000313|EMBL:ELK07919.1};
DE Flags: Fragment;
GN ORFNames=PAL_GLEAN10007152 {ECO:0000313|EMBL:ELK07919.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07919.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC {ECO:0000256|ARBA:ARBA00005597}.
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DR EMBL; KB030944; ELK07919.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K8A8; -.
DR STRING; 9402.L5K8A8; -.
DR eggNOG; KOG0018; Eukaryota.
DR InParanoid; L5K8A8; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03275; ABC_SMC1_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR028468; Smc1_ABC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR18937:SF147; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1B; 1.
DR PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 477..593
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 125..183
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 227..447
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 719..868
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELK07919.1"
SQ SEQUENCE 1164 AA; 135279 MW; B91AE3D213DB04D2 CRC64;
GKSNVMDALS FVMGEKTANL RVKNIQELIH GAHIGKPVSS SASVKIVYVE ESGKEKTFAR
IIRGGCSEFH FDDNPVSRSA YIVELEKIGI IVKAQNCLVF QGTVESISMK KPKERTQFFE
EISSSGDLIG EYEEKKRKLQ KAEEDAQFNF NKKKNVAAER KHAKLEKEEA ERYQSLLEEL
KINKIELQLF QLYHNEKKIH FLSTELEHMN RDLGATKESL SHHENIIKAN KKEHGMLTRQ
LQQTEKEIKS LEALLNQKRP QYIKAKENTS YHLKKLDVAK KSIKDSEKQC AKQEDDIKAL
ETELVDLDGA WKSFEKQIEE EVLRKVRDIE LEASQLENYK ELKEQVRKKV AIMTQQLEKL
QWEQKADKER LAFEKRRHAE VKENLKQIKE QIEDHKKRIE KLEEYAKTCI DCLKEKKQQE
EALVGEIEKT KSRISEINEE MTLIRSELQN AGIDNHEGKR QKKRAEVLEH LKRLYPDSVF
GRLLDLCHPI HKKYQLAVTK LFGRYMIAIV VTSEKVAREC IRFLKEERAE PETFLALDYL
DIKPINERLR EIKGCKMVID VIKTQFPQLK KVIQFVCGNG LVCETVEEAR HIAFNGPERR
KTVALDGTLF LKSGVISGGS SDLKYKARCW DEKELKNLRD RRTQLTQELK DLMKILRKEA
DLKQIQTLVQ GTHTRLKYSQ SELEIIKKKH LAAFYREQSQ LQSELLNIES QCTMLSEGIK
ERQQRIEEFQ GKIDKVEDDI FQHFCEEIGL ENIREFEKRH VKQQQEIDQK RLEFEKQKTR
LNIQLEYSRN QLKKKLNKIN TLKETIQKGR EDIDNLKKAE ENCLQVVDEL MEKWQQLKDI
FVTQNSDIEK IQAQIEEERK KFLAVDREVG KRQKEVIILQ SSLEQKRLEK HNMLLDCKVQ
DIEITLLLGS LDDIIEVELG TEAESTQATV DIYEKEEAIE VDYSSLREDL KALQSDKEIE
AHLKLLLQQV ASQEDVLLKT AAPNLRALEN LKTIRDKFQE STDVAIDQIY KKLCRNNSAQ
AFLSPENPEE PYLEGISYNC VAPGKRFMPM DNLSGGEKCV AALALLFAVH SFRPAPFFVL
DEVDAALDNT NIGKVSSYIK EQTQEQFQMI IISLKEEFYS KADALIGIYP EQDDCMFSRV
LTLDLSQYPD TEGQESSERP RESH
//
