ID   L5KA45_PTEAL            Unreviewed;       839 AA.
AC   L5KA45;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=Heat shock 70 kDa protein 4L {ECO:0000313|EMBL:ELK07646.1};
GN   ORFNames=PAL_GLEAN10013960 {ECO:0000313|EMBL:ELK07646.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07646.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC       {ECO:0000256|ARBA:ARBA00007381}.
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DR   EMBL; KB030951; ELK07646.1; -; Genomic_DNA.
DR   RefSeq; XP_006917822.1; XM_006917760.2.
DR   AlphaFoldDB; L5KA45; -.
DR   STRING; 9402.L5KA45; -.
DR   GeneID; 102897541; -.
DR   KEGG; pale:102897541; -.
DR   CTD; 22824; -.
DR   eggNOG; KOG0103; Eukaryota.
DR   InParanoid; L5KA45; -.
DR   OrthoDB; 276440at2759; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   CDD; cd11738; HSPA4L_NBD; 1.
DR   Gene3D; 1.20.1270.10; -; 2.
DR   Gene3D; 3.30.30.30; -; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018181; Heat_shock_70_CS.
DR   InterPro; IPR029048; HSP70_C_sf.
DR   InterPro; IPR029047; HSP70_peptide-bd_sf.
DR   InterPro; IPR013126; Hsp_70_fam.
DR   InterPro; IPR042708; HSPA4L_NBD.
DR   PANTHER; PTHR45639:SF5; HEAT SHOCK 70 KDA PROTEIN 4L; 1.
DR   PANTHER; PTHR45639; HSC70CB, ISOFORM G-RELATED; 1.
DR   Pfam; PF00012; HSP70; 1.
DR   PRINTS; PR00301; HEATSHOCK70.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 2.
DR   SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR   PROSITE; PS00329; HSP70_2; 1.
DR   PROSITE; PS01036; HSP70_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Stress response {ECO:0000313|EMBL:ELK07646.1}.
FT   REGION          504..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          792..839
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        807..821
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        822..839
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   839 AA;  94704 MW;  57BBE9AC4DFD3E60 CRC64;
     MSVVGIDLGF LNCYIAVARS GGIETIANEY SDRCTPACIS LGSRTRAIGN AAKSQIVTNV
     RNTIHGFKKL HGRSFDDPIV QTERIRLPYE LQKMPNGSAG VKVRYLEEER PFAIEQVTGM
     LLAKLKETSE NALKKPVADC VISIPSFFTD AERRSVMAAA QVAGLNCLRL MNETTAVALA
     YGIYKQDLPP LDEKPRNVIF IDMGHSAYQV SICAFNKGKL KVLATTFDPY LGGRNFDEAL
     VDYFCDEFKT KYKINVKENS RALLRLYQEC EKLKKLMSAN ASDLPLNIEC FMNDLDVSSK
     MNRAQFEQLC ASLFARVEPP LKAVMEQANL QREDISSIEI VGGATRIPAV KEQITKFFLK
     DISTTLNADE AVARGCALQC AILSPAFKVR EFSITDIVPY SITLRWKTSF EDGTGECEVF
     CKNHPAPFSK VITFHKKEPF ELEAFYTNLN EVPYPDPRIG SFTIQNIFPQ SDGDSSKVKV
     KVRINIHGIF SVASASVIEK QNIEGDHNDA PMETETSFKS ESKDDVDKMQ VDQEEGHQKC
     HAEHTPEEEI DHTGTKTKSA PSDKQDRLNQ TIKKGKVKSI ELPIQSSLCR QLGQDLLNSY
     IENEGKMIMQ DKLEKERNDA KNAVEEYVYD FRDKLGTLYE KFITQEDFSK LSAILEDTEN
     WLYEEGEDQP KQIYVDKLQE LKKYGQPIQI RYMEHEERPK ALNDLGKKIQ LVMKVIEAYR
     NKDEKYDHLD PAEMEKVEKY ISEAMSWLNS KMNAQNKLSL TQDPVVKVSE IVTKSKELDN
     FCNPIIYKPK PKVEVAEDPA KANSEHNGPM DGQSGTETKP DPTKDNSLHT KSSGEMEVD
//