ID   L5KAK7_PTEAL            Unreviewed;       826 AA.
AC   L5KAK7;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=Interleukin-17 receptor D {ECO:0000313|EMBL:ELK07806.1};
GN   ORFNames=PAL_GLEAN10022185 {ECO:0000313|EMBL:ELK07806.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK07806.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR   EMBL; KB030947; ELK07806.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5KAK7; -.
DR   STRING; 9402.L5KAK7; -.
DR   eggNOG; ENOG502QV61; Eukaryota.
DR   InParanoid; L5KAK7; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   Gene3D; 3.40.50.11530; -; 1.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR031951; IL17R_D_N.
DR   InterPro; IPR013568; SEFIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR15583; INTERLEUKIN-17 RECEPTOR; 1.
DR   PANTHER; PTHR15583:SF14; INTERLEUKIN-17 RECEPTOR D; 1.
DR   Pfam; PF16742; IL17R_D_N; 1.
DR   Pfam; PF08357; SEFIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS51534; SEFIR; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000313|EMBL:ELK07806.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..826
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003969023"
FT   DOMAIN          356..510
FT                   /note="SEFIR"
FT                   /evidence="ECO:0000259|PROSITE:PS51534"
FT   REGION          686..708
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          786..826
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        686..701
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   826 AA;  91829 MW;  9308B611F1367E12 CRC64;
     MAPWLQLCSV FFTVNACLNG SQLAVAAGGS SRARGGADTC GWRGMGPASR NSGLHNITFR
     YDNCTTYLNP VGKHVIADAQ NITISQYACH DQVAVTIFWS PGALGIEFLK GFRVILEELK
     SEGRQCQQLI LKDPKQLNSS FKRTVMESQP FLNMKFETDY FVKIVPFPSL KNESNYHPFF
     FRTRACDLLL QPDNLACKPY WKPRNLNITQ HGLDMQVSFD HAPHTFGFRF FYLHYKLKHE
     GPFKRKTCKQ EQNTETTSCL LQNVSPGDYI IELVDDTNTT RKVMHYALKP VHSPWAGPIR
     AVAITVPLVV ISAFATLLTV MCRKKQQENI YSHLDEESSE SSTYTTALPR DRLRPRPKVF
     LCYSSKDGQN HMNVVQCFAY FLQDFCGCEV ALDLWEDFSL CREGQREWVI QKIHESQFII
     VVCSKGMKYF VDKKNYKHKG GGRGSGKGEL FLVAVSAIAE KLRQAKQSSS AALSKFIAVY
     FDYSCEGDVP GILDLSTKYK LMDNLPQLCS HLHSQDHSLP EPGQHPGHVS RRNYFRSKSG
     RSLYVAICNM HQFIDEEPDW FEKQFVPFHP PLLRYREPVL EKFDSGLVLN DVMCKPGPES
     DFCLKADVAI PGVPADSHLE SQQLGLNEDA EAGASPGDGS VLQPLLHTVK AVSPLGMPRD
     SGIYDSSVPS SELSLPLMEG LLADQTETSS LTESVSSSSG LGEEDPPGLP SKLLTSGACK
     AEPGCCSYTA FTLGTMVLTS ANRTNMKEDA EKHPEWEVGA VAQAGPIMVP YPPRCGDWFR
     ATNWPGQARP GHGLPQSYPN SSEAAEKMLG GTWVQSSKDG TPECEV
//