ID L5KEJ1_PTEAL Unreviewed; 963 AA.
AC L5KEJ1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Rab effector MyRIP {ECO:0000313|EMBL:ELK10099.1};
GN ORFNames=PAL_GLEAN10007745 {ECO:0000313|EMBL:ELK10099.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK10099.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB030759; ELK10099.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KEJ1; -.
DR STRING; 9402.L5KEJ1; -.
DR InParanoid; L5KEJ1; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR006788; Myrip/Melanophilin.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14555; MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED; 1.
DR PANTHER; PTHR14555:SF6; RAB EFFECTOR MYRIP; 1.
DR Pfam; PF02318; FYVE_2; 2.
DR Pfam; PF04698; Rab_eff_C; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50916; RABBD; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 4..172
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT REGION 294..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 868..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..709
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 963 AA; 106009 MW; 0A4FF1BE18EC62DC CRC64;
MGRKLDLSGL TDDETEHVLQ VVQRDFNLRK KEEERLRPDN YTNAGILEES TSMGNAFNVM
DNQINQVSHE GSWKEREESG GSLDGELKQK LDEEGSKCSI LSKHQKFVEH CCMRCCSPFT
FLVNSKRRCG DCAFNVCKSC CSYQKHEKVW VCCVCQQARL LRTQSLEWFY NNVKSRFKRF
GSAKVLKNLY RKHRLESGAC FDILGGSFFE ANLENEGSIS GSESTFYKQS EGHSMMDTLA
VALRVAEEAI EEAISKAEAY GDSLVQPPSS SLWGGVGQGG GERVQVVRKP ASQEQCPTSP
CICGQDSQKD KQHEASYLRD HKEELTEELA TTILQKIIRK QKSRSEQQMG EEPGWSQPQS
CSAKAADEGT TASAGGHRAS STFWSAFSLT RGGAPKTSSL EAASRQPGNQ AQQPREESAL
PSWTSVDRLD DTDLAPVLQS PDGNWVALKD GTLPPTRLLA KPKSGTFQAL EVASSVTSAY
DEMGSDSEED FDWSEALSTL CPRPRGLTRK PQPQLTQAQG SDQGPLAISA SSRLSPYPEA
MCSDSETSSA GSSREAGHRA RLSWVQRKAP RNPAAEKMRL QGELDVNFNL QAAGRETSDS
SEPEEAPHAA DRRARRWRRA RVGSEEPSKE PPSPDAHSQD LDTHQVSGDL SETELSSEAR
HPQMGADITE EKVRSRFFKL AMKMSEKDTS SGEDQESEPK TESENQKESV SSEDNSQSVQ
EELKKKYSAV SLCNISTEVL KVINATEELI AESAGSWEFP PGFPDREKGT FPLGTDQVRL
DEQLTSLEEN VYLAAGTVYG LEGQLNELED AARCIHSGTG ETELADLEDQ VATAAAQVHH
AELQITDIES RISALTVAGL NIAPCGRLTR KRDQKQRNQV QTIDTSRQQR RKLPAPPVKA
ENTEASSVTT MKTFNRNFIL QGSSTNKTKE SKSTTEDAMV NVISALIPVT STVVGTSILQ
LPY
//
