ID L5KK12_PTEAL Unreviewed; 403 AA.
AC L5KK12;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=CD226 antigen {ECO:0000313|EMBL:ELK11121.1};
GN ORFNames=PAL_GLEAN10017155 {ECO:0000313|EMBL:ELK11121.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK11121.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030713; ELK11121.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KK12; -.
DR STRING; 9402.L5KK12; -.
DR eggNOG; ENOG502RY5X; Eukaryota.
DR InParanoid; L5KK12; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0002729; P:positive regulation of natural killer cell cytokine production; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR042842; CD226.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR47011; CD226 ANTIGEN; 1.
DR PANTHER; PTHR47011:SF1; CD226 ANTIGEN; 1.
DR Pfam; PF07686; V-set; 2.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..403
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003969281"
FT TRANSMEM 251..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..126
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 127..239
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 332..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 45044 MW; FAA0FF389222F175 CRC64;
MDYLIFLLAI LHVYKALCAE IFWDTTVKLA ENTTLECVYP LVGTFTQVEW FKISATERES
IAIFNPTYGM VIRTPYAERV YFLNSSMALN DMTLSFHNAS EADVGFYSCI LETFPQGSWE
KTVQVVPSES FEVAVSSNSH VVSESGKNVT LTCELPMKRP LQQVTWEKIQ SHQIDRLTSC
NLSQGRGHTS KYRRQVLSNC SQWVTRAFIT LPHVTARDAG LYRCSSKASS GDNETFVIRL
AVTDGKTDNQ YIHFMAGGTV LLLLFVIIIA TIIVLYNRFS TLVILPMLKI LLKRRLLFRE
HTQLACHPHA TEMLFSPSLA LIPWSIRDVP TGTEEARTNH GSLQGSECPP RPGATQRPTP
GLCPPPGSLP LGRNSSAAKR MWLRTCVAPV SEAVCALKKL FSM
//
