ID L5KL13_PTEAL Unreviewed; 591 AA.
AC L5KL13;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 2 {ECO:0000313|EMBL:ELK12012.1};
DE Flags: Fragment;
GN ORFNames=PAL_GLEAN10015695 {ECO:0000313|EMBL:ELK12012.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12012.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030666; ELK12012.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KL13; -.
DR STRING; 9402.L5KL13; -.
DR eggNOG; KOG3561; Eukaryota.
DR InParanoid; L5KL13; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF48; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Receptor {ECO:0000313|EMBL:ELK12012.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 62..115
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 133..198
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 333..382
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 36..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ELK12012.1"
SQ SEQUENCE 591 AA; 66349 MW; A054B9E9C94A0E8C CRC64;
EALLDDSQYI APMVSNQMSP WTKPIAIGSF SPHVTEFPRK RKGSDSDPSQ VEDGEQQVKM
KSFREAHSQT EKRRRDKMNN LIEELSAMLP QCKPVARKLD KLTVLRMAVQ YLKSLKGMTN
FYAGDNYRPS FIQENELRHL ILKTAEGFLF VVGCERGKIL FVSKSVSKIL NYDQASLTGQ
SFFDFLHPKD VAKVKEQLSS SDISPREKLI DAKTGFQVNS NFQTGRTRVC SGSRRSFFCR
IKSCKVSVKE EDECLPNSKK KDHRKFCTIH CTGYLRSWPP NIIGMEEEKD SQKDSNFTCL
IAIGRLHPYI VPQNSGEMIK VKPTEFITRF AMNGKFVYVD QRATAILGYL PQELLGTSCY
EYFHQDDHSN LTDKHKAVLQ SKEKIFTDSY KFRAKDGSFV TLKSQWFSFT NPWTKELEYI
VSINTLVLGH SENGEVSLLP CSSQSLEESS RQSCISVPGM STGTVLGAGS IGTDIANEVL
DLQRLQFSSS LGDSSPTDLM KDTHTINFRN MSNKELIPLS PSEVGELEAT MQNHSTADPP
SHEPLLGDGA QLDFDALCDN NDTAIAAFMN YLEAEGGLGD PGDFSDIHWT L
//
