ID L5KMY2_PTEAL Unreviewed; 687 AA.
AC L5KMY2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Calcium/calmodulin-dependent protein kinase type II beta chain {ECO:0000313|EMBL:ELK13029.1};
GN ORFNames=PAL_GLEAN10002264 {ECO:0000313|EMBL:ELK13029.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK13029.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB030634; ELK13029.1; -; Genomic_DNA.
DR STRING; 9402.L5KMY2; -.
DR InParanoid; L5KMY2; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14086; STKc_CaMKII; 1.
DR Gene3D; 3.10.450.50; -; 1.
DR Gene3D; 6.10.140.620; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR013543; Ca/CaM-dep_prot_kinase-assoc.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24347:SF403; CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETA; 1.
DR PANTHER; PTHR24347; SERINE/THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF08332; CaMKII_AD; 1.
DR Pfam; PF00069; Pkinase; 2.
DR SUPFAM; SSF54427; NTF2-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ELK13029.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transferase {ECO:0000313|EMBL:ELK13029.1}.
FT DOMAIN 119..375
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 475..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..502
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 76204 MW; 49BDDC4EC6760BCE CRC64;
MKTRPLLQQT CPSGTDGAEA TQTLQRSPLR FPVLILGQPL RLFRVTEKNT HAQSDRVDVR
FCDFRVEVIT LPGLPEDQCR CFLAQVDGPS LFKAAAPGSS PVTLSSLPGK GQATGPQLPQ
SLTTPPKGAF SVVRRCVKLC TGHEYAAKII NTKKLSARDH QKLEREARIC RLLKHSNIVR
LHDSISEEGF HYLVFDLHCI QQILEAVLHC HQMGVVHRDL KFLSPSRPRL WTTPLAITAL
QPENLLLASK CKGAAVKLAD FGLAIEVQGD QQAWFGFAGT PGYLSPEVLR KEAYGKPVDI
WACGVILYIL LVGYPPFWDE DQHKLYQQIK AGAYDFPSPE WDTVTPEAKN LINQMLTINP
AKRITAHEAL KHPWVCQRST VASMMHRQET VECLKKFNAR RKLKGAILTT MLATRNFSAA
KSLLNKKADG VKEPQTTVIH NPVDGIKESS DSAHTTIEDE DTRAPRISDI LNTVRRGSGT
PEAQGPPPCL SLALPGPPPA PSRKQDIIKI TEQLIEAVNN GDFEAYAKIC DPGLTSFEPE
ALGNLVEGMD FHRFYFENLL AKNSKPIHTT ILNPHVHVIG EDAACIAYIR LTQYIDGQGR
PRTSQSEETR VWHRRDGKWQ NVHFHCSGAP GXXXXXXXXX XXXXARPLPG LGRGRPQPAL
HRPGETPEVG RGRPSWEADP PACRFQS
//
