ID L5KNJ6_PTEAL Unreviewed; 2347 AA.
AC L5KNJ6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Chondroitin sulfate proteoglycan 4 {ECO:0000313|EMBL:ELK12183.1};
GN ORFNames=PAL_GLEAN10009661 {ECO:0000313|EMBL:ELK12183.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12183.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR EMBL; KB030662; ELK12183.1; -; Genomic_DNA.
DR STRING; 9402.L5KNJ6; -.
DR eggNOG; KOG3597; Eukaryota.
DR InParanoid; L5KNJ6; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00110; LamG; 2.
DR Gene3D; 2.60.120.200; -; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR039005; CSPG_rpt.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR45739; MATRIX PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45739:SF8; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF16184; Cadherin_3; 14.
DR Pfam; PF02210; Laminin_G_2; 2.
DR SMART; SM00282; LamG; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR PROSITE; PS51854; CSPG; 14.
DR PROSITE; PS50025; LAM_G_DOMAIN; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2220..2245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..151
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 161..339
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REPEAT 380..476
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 505..600
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 734..829
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 849..943
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 976..1068
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1084..1175
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1195..1293
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1311..1402
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1426..1516
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1533..1633
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1658..1757
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1787..1881
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 1898..1986
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
FT REPEAT 2002..2101
FT /note="CSPG"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01201"
SQ SEQUENCE 2347 AA; 263510 MW; 8DAB25581C785A35 CRC64;
MALPAPVQPP NWLGAAPLTR LRVQATGRVG PVQVRVNLGA GEQVRLSEQR LHVDDLTWHL
VELYCVKDTI SLIVDKHYET TRQVTGGMHN LHFQHGVYVG GHSGLDVPYL VEEFPNFRGC
VEDVVFNRRE ILTSLRSYPG FKKVYEVSLG CSDEFFAGEG EAINFFSSRS YVTFPQWKVQ
GEGLLEFALQ TGTQQALILF QSGREGEFVA LEIVKGVLRA HVGRSKSNTQ LSSFSLVSDD
KWHVIQLRFT ERHLDLMVDE QGVRASLPLK GKLFVSEGPL FVGGLDNHKR EEVKKLELAS
VPRKSRGISF KGCLKGLEVN SEKKALKDAL VSKDISVGCK MKSRDAENLS ITTTENALRS
EVLLPTAIPE TGKLFLQDAS SSFLVLNNLE VQEGGQALLE QRHVKMGMQF KDLGIHHSQI
LFKIKEMPIH GFLRLAVSPE QEMEKAFTLL DLGQGKVRYI HDGSEEARDY FTFSVSSKSK
EEMPLYLQGH VPYVFNIIVI PVNDPPYLKL PEGNLLLLFE NSKKRLTPNI IHVSDPDTDS
LNLSFLVLGN FDSDAGFLEN TNDPGRAINS FTHGDLKDGN IFYVHRGHRN SRILLRASDG
ELVSNTVVLR VMAVPLDFEV ANRTGVVVRQ GDTVLITQSN LSVAVNGEHH EMETHYIITR
LPQFGQIQRQ ESSGEWKQVS TFSQHSIDRS QIRYCSTFKE LQLENVTDYF KFKVNIEGKM
SGELMFPVTV QWLKFTLLKN VPLEIDKMNR QVLNCDHLQA VTEGVEVAEK ELHFKLQTPP
KKGKLLLGNK ILKTNSIFSQ HDITDSKVSY EPQERPREDT QDTFRFSIVA KHIESKDYTF
TINLKTAKTN IILTNRGLFV KEGEGKLITK SELFAQTLDN QTFQYKLTRS PQHGKLKLVN
FSDSLGSHDN ITTFTNEDIV GERLMYVHDD SETQWDEFLL VASTMSQEGV VRGLDMEHLS
TELKVIISVG LKNDERPVRV VDKVFHVVRN GQRLLTLADL CYHDPDSDFD DGQLLYTRRG
IPNGDLVWTS DPTQKLYQFR QDDLQAGRVL FRHQGADSAR FVLFVTDGIH YTSSLLEVRV
SDPYIQLANN TGLLVQRGKD CRLTAANLSV TTNQDIRTNH EIEFHIVQPA KHGRVLVNNS
VSHSFTQHDL MQGHVVYRHD GSGNFDVFNL TVKVKETYLE VSVYVRVSLE NHQQPTQVLH
SKTLVIEEGK SVKLGRGKLQ AVHEDNIPSE ATFIVRTPPT HGYLRKSLLE ESSLGANEKS
PLIFTQQDID DGNIYYVQTA PDQQKDRFLL DVMNGFQAVS GVEILVDIVP KQIPLEVRNF
TVQEGGSRAL LEDDLKIPSK YFEGLDCEFV LLKPPKHGYV ENSHFPRVKL MKFTRKQVEN
ELIYYVHDDS EELLDNFTVF ANSLELGKQS FPQTLFVTVE SINDEAPVIT ANKILQVWVN
SVTEITSSDL CAEDGDSSPQ DLAYWVTPPS NGHLALKSFP GQSIQNFTQV QINNGQLVFV
HTGAMSGGFN FQVTDGLNFA PRQIFSITAR ALIISLEVNR GLSIFPGSMK PLSSRDLRAV
TNDEDSAGNR TITFMVISSP RLGKLMRVNP DNSTEHVSVF TQDLVNEQLI LYQHVDHENT
GRTVEDSFMF TVSSPPAALG PEKFHITISC EINEPGRQSR LLANTGAAVK EGDKVLIDQS
KLDASNFLLK LPESQRSSYE IWFQVTSLPH HGTIMVGERN ITKGKPYFPQ YIINKFGITY
VHDDSESLAD NFTFAVWPNP KNKSVAKPEA DFLEETFNIT ISPINDQTPE LKTKELRLKV
LQGSRLVVGP DKLKVEDLDN SPEEIRYTII RSPNNGFLSM AHHLDTPVHH FTQANIDDSQ
VWFTQDGSPS SGAFYFSVTD GQHRPLYKLF HLDVIPVSIT LVNLTDLLLP QGQTTISITN
AHLSAMTNGR IPQIMYKITC PLQHGHLLIE NQMVVSFRQE DLDSGRLSYH MTNLTASEDQ
LQFSVFTSES NLTGLTLNIR VQPLLQVLSD LTVTNRVAYQ LTRKDLDASE LANRTNSDPK
FEVTEPPVHG RLVRRVGHGT LMEDATLFTQ WDIDQGLLML DSHANLTGTD ILNDSFTFLL
RADHVQPAIG YLPFSIVPPD ALLLQRFTPD VSLLVTADNL VTSALSQEKP VVSSGPMAQT
ETLGKLTQIR WQKPDPWGRH SGEGPTVDGK VSPTGVIWPQ AATKDSPWAP TQPRKSSYPL
MVIIPLAAVV FLLLVTVVAL CAWLLGQKVE KRKPLIKPQT DLEPTTPSPR PERSITVPTV
TVTPLLKSSS SPQVSLFRAL PCEQMASPVT EPVEKCAPWE TWVNLDPDMV KLCRQTNPTL
KHNQYWV
//
