ID   L5KPQ3_PTEAL            Unreviewed;       812 AA.
AC   L5KPQ3;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Leucine-rich repeat-containing protein KIAA0644 {ECO:0000313|EMBL:ELK12618.1};
GN   ORFNames=PAL_GLEAN10021870 {ECO:0000313|EMBL:ELK12618.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12618.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB030660; ELK12618.1; -; Genomic_DNA.
DR   RefSeq; XP_006912089.1; XM_006912027.2.
DR   AlphaFoldDB; L5KPQ3; -.
DR   STRING; 9402.L5KPQ3; -.
DR   GeneID; 102884998; -.
DR   KEGG; pale:102884998; -.
DR   CTD; 9865; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   InParanoid; L5KPQ3; -.
DR   OrthoDB; 4599366at2759; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR000483; Cys-rich_flank_reg_C.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR   PANTHER; PTHR24373:SF307; TLR4 INTERACTOR WITH LEUCINE RICH REPEATS; 1.
DR   Pfam; PF13855; LRR_8; 4.
DR   SMART; SM00365; LRR_SD22; 5.
DR   SMART; SM00369; LRR_TYP; 11.
DR   SMART; SM00082; LRRCT; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..812
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003969413"
FT   TRANSMEM        696..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          359..415
FT                   /note="LRRCT"
FT                   /evidence="ECO:0000259|SMART:SM00082"
FT   REGION          410..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..545
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   812 AA;  88746 MW;  847DE2AA6B3C92D2 CRC64;
     MEAARAVRFL LVVCGCLTLP PRAEPVCPER CDCQHPQHLL CTNRGLRAVP KTSSLPSPLD
     VLTYSLGGNF ITNITAFDFH RLGQLRRLDL QYNQIRSLHP KTFEKLSRLE ELYLGNNLLQ
     ALAPGTLAPL RKLRILYANG NEIGRLSRGS FEGLESLVKL RLDGNALGAL PDAVFAPLGN
     LLYLHLESNR IRFLGKNVFA QLGKLRFLNL SANELQPSLR HAATFAPLRS LSTLILSANS
     LQHLGPRVFQ HLPRLGLLSL RGNQLTNLAP EAFWGLEALR ELRLEGNRLS QLPVALLEPL
     HSLEALDLSG NELSALHPTA FGHLGRLREL SLRDNALSAL SGDIFAASPA LYRLDLDGNG
     WTCDCRLRGL KRWMGDWHSQ GRLLTVFVQC RHPPALRGKY LDYLDDQQLQ NGTCADPPPS
     VSPTADGERR PLPTATREEM APPAGGLTEE MPPQPQSQQR GRLLPGAAWD GAARELLGNR
     SAVRLSRRGP GLQQPGPSAA AAAGQAPPPL DLLEKPERQR PTPDDPAPAE PTSTAAPASA
     PLPVGDPWQR AVKQLLAAQQ QESAAQSDGG VGLPPLVSDP CDFNKFVLCN LTVEAVGSDS
     ASVRWAVREH RSPRPLGGAR FRLLFDRFGQ QPKFHRFVYL PERSDSATLR ELRGDTPYLV
     CVEGVLGGRV CPVAPRDHCA GLVTLPEPGS RSGVDYQLLT LALLAVNALL VLLALAAWGS
     RWLRRKLRAR RKGGAPVHVR HMYSTRRPLR SMGTGVSADF SGFQSHRPRT TVCALSEADL
     IEFPCDRFMD SGGGGGGGSL RREDHLLQRF AD
//