ID L5KPX5_PTEAL Unreviewed; 501 AA.
AC L5KPX5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|EMBL:ELK12971.1};
GN ORFNames=PAL_GLEAN10008016 {ECO:0000313|EMBL:ELK12971.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK12971.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030636; ELK12971.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KPX5; -.
DR STRING; 9402.L5KPX5; -.
DR InParanoid; L5KPX5; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR CDD; cd13738; SPRY_PRY_TRIM14; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR044116; SPRY_PRY_TRIM14.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR25465:SF11; B BOX-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 22..61
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 308..501
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 501 AA; 56955 MW; 93C52BD4C9073581 CRC64;
MANAAGLSGT SKGPGHVESE NSYGLRCPEH DDRVAELFCR RCRRCVCTLC PVLGAHRGHP
VGLALEEAVH VQKFIQECLK QLAAKNQQQV GNRRQIEDTA EHLKANPAAP HVLAPLRREH
GITGEPAHPM PVQTPGSNLR VGHTDAWAEE RGWPMFGLAY AHAESSKTWL TEKFSELRLL
LDEEEVMAKK FIDKHMQLTL QVYSEQIKSC GEQIDLLNSL SNRVWSISQE PSPIQLLQEF
TATERELKQQ MSREELCHPV PQSFEPVKSF FKGLVEAMRR MLQMPLDVRL KENMNCQLSS
SSSTKLDFLL KTSFSPERSL FLKYARTPTL DPDTMHVRLR LSADRLTVRC ALLGRLGPTP
ALRFDALWQV LGRDCFAAGR HYWEVDVQEA GAGWWVGVAY ASLRRHGESA AARLGCNRQS
WCLKRYDLEY WAFHDCQRSR LQPHHDPDRL GIFLDYEAGI LSFYDVSGSM RHLHTFRAAF
QEPLYPALRL WEGAISIPRL P
//
