ID L5KRD2_PTEAL Unreviewed; 2410 AA.
AC L5KRD2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Neuroblastoma-amplified sequence {ECO:0000313|EMBL:ELK13989.1};
GN ORFNames=PAL_GLEAN10020154 {ECO:0000313|EMBL:ELK13989.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK13989.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB030580; ELK13989.1; -; Genomic_DNA.
DR STRING; 9402.L5KRD2; -.
DR eggNOG; KOG1797; Eukaryota.
DR InParanoid; L5KRD2; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029145; NBAS_N.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR013244; Sec39_domain.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR15922:SF2; NBAS SUBUNIT OF NRZ TETHERING COMPLEX; 1.
DR PANTHER; PTHR15922; NEUROBLASTOMA-AMPLIFIED SEQUENCE; 1.
DR Pfam; PF15492; Nbas_N; 1.
DR Pfam; PF08314; Sec39; 2.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 90..371
FT /note="Neuroblastoma-amplified sequence N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15492"
FT DOMAIN 724..1007
FT /note="Sec39"
FT /evidence="ECO:0000259|Pfam:PF08314"
FT DOMAIN 1017..1365
FT /note="Sec39"
FT /evidence="ECO:0000259|Pfam:PF08314"
FT REGION 457..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2410 AA; 272555 MW; 15CE08F3227CB333 CRC64;
MAASESVAAV IPGTVEGEEE TILYDLLVNT EWPPETEVQP RGNRKHDESF IITKAIRDRL
LFLRQYIWYS PAPFLLPDGL VRLVNKQINW HMALASNGKL LAAVQDQCVE IRSAKDDFTS
IIGKCQVPKD PKPQWRRVAW SYDCTLLACA ESTGTVRVFD LMGSELFVIA PASNLAGDLS
YAIAGLIFLE YKASAQWSAE LLVINYRGEL RSYLVSVGTN QSYRESHCFN FGSHYAHGIN
TAVYHPGYRL LLVGGCETAG VGISKASSCG LSAWRVLSGS PYYKQVTNGG DTVTAVPKTL
GLLRMLSAKF YSRPGQEQDG IFRMSLSPDG SLLAAIHFSG KLSIWAIPSL KQQGEWHQNE
QPGFDDLNPA WRLSAEKRKK IKDKGSFYPL IDVNWWADNA VTLARCSGAL TVSSVKTLKN
LLGKSCEWFE PSPQVTATHD GGFLSLECEI KLAPKRSRLE TRGGEDDREE DSDSDQEMSA
KARYFGYVKQ GLYLVTEMER FAPLRRRPRT FTKNYRLVSL RSTTPEELYQ RKIESEEYEE
ALSLAQTYGL DTDLVYQRQW RKSAVNIASI QNYLSKIKKR SWVLHECLER VPENVDAAKE
LLQYGLKGTD LEVLLALGKG SDDGRFALPD EVDIDGVSYE DLLPPDEEPA AKKKKALKKR
RELLKLVNFS KLTLEQKELC RYRLRLLTYL DRLATYEEIL GVSHASEQRY DAEFFKKFRN
QNIVLSARTY ARESNVQALE ILFTYHGSDL LPHRLAILSN FPETTSPHEY SFLLPEACYD
GDSLMIIPWH ERKHRDKDWC EESECRMAAE PSLQDDSEFL YAAQPELLRY KATQLAVEDV
IDWYQTRAEE IEHYARQVDC ALSLVRLGME RNVPDLLVLC DNLVTLEALV YEAGCDLTLT
LKELQQMKDI EKLRLLMNTC SEDKYVTSAY QWMVPFLHRC EKQSPGVAKE LLKEYLVTLA
KGDLKLPLKI FQHSKPDLQK KIIPDQDQLM AVALECIYNC ERSDQLSLCY DILECLPQRG
YGDKTEITTT LHDMVDQLEQ ILSVSELLEK HGLEKPISFV KNTQSSSEEA QKLMVRLTRH
TGRKQPPASE SHWRMLLQDM LAMQQNVYTC LDPAACYEIF TESLLCSSRL ENIHLAGQMM
HCSACSMNPP PSVAQKGKTQ YRVSYEKSID LVLAASREYF NSSTSLTDSC MDLARCCLQL
ITDRPAVIQE ELDLIQALGC LEEFGVKILP LQVRLCSDRV SLIQECICQS PTCYKQSAQL
LGLAELLRVA GEDPEERRGQ VLILLVEQAL RFHDYKAANV HCQELMATGY SKSWDVCSQL
GQSEGYQDLA TRQELMAFAL THCPPSSIEL LLAASSSLQT EILYRRVNFQ IHPEGGDEVS
VSGSNSADLF HWTTATTMKV LSNTTTTTKA VLQAVSDGQW WKKSLTYLRP LQGQEFDGAY
RIGTIANEDL EKQGCHPFYE SVISNPFVTE SEVTYDTYQH VPGESFAEVL LRTGKLAETK
SEGEEVFPTT EVLLQLASEA LPNDMTLALA YLLALPQVLD ANRCFEKQAH SALSLQLAAY
YYSLQIYAQL APCFRDKCHP LYRADPKELI KMVTRHVTRY GYEAWPEDLV ALTKQLHYYN
ERLLDFTQAQ VLQGLRKGVD VQRFTADDQY KRETILGLAE TLEENVYSVA LSLAQRYGVS
RWEIFMTHLE FLFTDSGLST VEIENRAQTL HLFETLKTDP ETFHRHMVKY IYPSIDGFDH
ERLLYYFTLL ESFGCADFGK YAIKPETHIR LLKKFKVVAS GLNYKKLTDE NMNPLKALEP
VLSSQNILSI SKLVPKIPDK DGRMLSPSSL YTIWLQKLFW TGDPHLARPS PEPSSAWLHA
CEVCVKYFDR LHPADLITVV DAITFSPKAV TKLSVEERKE MTRMAIKTVK HFIEKPKKRN
LEENIEEAND SKMTYIDTLN HLEKSLAHLE TLNHSFIVSL KNSEQEILQK YSNLYDLSRS
ESGKLHDQAV AMCLDGQPLR MIQQLLEVAV GPLDLSPKDI VQSAIMKIIS ALSGSSADLG
GPGDPLQVLE GVVAAVHASV DKGEELVSSE DLLEWLRPFC ADDALPVRPR IYVLQILGQS
FHLSEEDSKL LVFFRTETIL KATWPQRQVD ITDIENEENR YSLFVELLES SHQEAEFQHL
VLLLQAWPPM SRDYVSSITN NPWMRLATAM LTRCTVENKE GLGSEVLKIC RSLYNTKQML
PAEGLDWMAS QGTPLLSALR GLRTCEEVQL RLSVYCFIRS TQFTTFQSPS SLGVGKKGVK
ELSALLWNQS LLLPSLKLLL EGQDETLHAV ALEHVASVAE VNDSNCDREL LSLLLDAKLL
GPCVSTAFYP RIVEHLLASQ QGRWDAEELA RDLREAGHEA EAGSLLLAAR GTHRALRTFS
TALSAGRHWV
//
