ID L5KRN7_PTEAL Unreviewed; 622 AA.
AC L5KRN7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Large ribosomal subunit protein eL19 {ECO:0000256|ARBA:ARBA00035217};
DE AltName: Full=60S ribosomal protein L19 {ECO:0000256|ARBA:ARBA00035324};
GN ORFNames=PAL_GLEAN10012880 {ECO:0000313|EMBL:ELK13621.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK13621.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000256|ARBA:ARBA00011133}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat EBI family.
CC {ECO:0000256|ARBA:ARBA00025741}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL19 family.
CC {ECO:0000256|ARBA:ARBA00011082}.
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DR EMBL; KB030623; ELK13621.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KRN7; -.
DR STRING; 9402.L5KRN7; -.
DR eggNOG; KOG0273; Eukaryota.
DR InParanoid; L5KRN7; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.10.1650.10; -; 1.
DR Gene3D; 1.20.960.30; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR035970; 60S_ribosomal_eL19_sf.
DR InterPro; IPR045183; Ebi-like.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR000196; Ribosomal_eL19_dom.
DR InterPro; IPR015972; Ribosomal_eL19_dom1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22846:SF40; F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1; 1.
DR PANTHER; PTHR22846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF01280; Ribosomal_L19e; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01416; Ribosomal_L19e; 1.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF48140; Ribosomal protein L19 (L19e); 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 163..204
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 226..250
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 260..301
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 343..384
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 385..435
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 436..477
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 515..620
FT /note="Large ribosomal subunit protein eL19"
FT /evidence="ECO:0000259|SMART:SM01416"
FT REGION 117..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 67949 MW; 8E4F88B33042BB52 CRC64;
MGRSVGLWNW GDEPGHIGFS HSAFTFGIES HISQSNINGA LVPPAALISI IQKGLQYVEA
EVSINEDGTL FDGRPIESLS LIDAVMPDVV QTRQQAYRDK LAQQQAAAAA AAAAATNQQG
SAKNGENTAN GEENGAHTIA NNHTDMMEVD GDVEIPPNKA VVLRGHESEV FICAWNPVSD
LLASGSGDST ARIWNLSENS TSGSTQLVLR HCIREGGQDV PSNKDVTSLD WNSEGTLLAT
GSYDGFARIW TKDGNLASTL GQHKGPIFAL KWNKKGNFIL SAGVDKTTII WDAHTGEAKQ
QFPFHSAPAL DVDWQSNNTF ASCSTDMCIH VCKLGQDRPI KTFQGHTNEV NAIKWDPTGN
LLASCSDDMT LKIWSMKQDN CVHDLQAHNK EIYTIKWSPT GPGTNNPNAN LMLASASFDS
TVRLWDVDRG ICIHTLTKHQ EPVYSVAFSP DGRYLASGSF DKCVHIWNTQ TGALVHSYRG
TGGIFEVCWN AAGDKVGASA SDGSRYLPIG FKRGLRCGKK KVWLDRDETS EITSANSCQQ
IQKLIKDEFP SSMPEKHLGL QEGQVYGHRL RLTGLRQGSM QAASEELLQV KEEEIIKTLS
EEGDQEIKHH LFYLYIVALV II
//
