ID L5KS06_PTEAL Unreviewed; 435 AA.
AC L5KS06;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Matrilin-3 {ECO:0000313|EMBL:ELK14005.1};
GN ORFNames=PAL_GLEAN10020180 {ECO:0000313|EMBL:ELK14005.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK14005.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030580; ELK14005.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KS06; -.
DR STRING; 9402.L5KS06; -.
DR eggNOG; KOG1217; Eukaryota.
DR InParanoid; L5KS06; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF12; MATRILIN-3; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 1.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 39..214
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 435 AA; 47607 MW; 18E002C4F335F55C CRC64;
MVYSSPGVRN RPISEYGQIQ SPLFPTPFLA GVCKSRPLDL VFIIDSSRSV RPLEFTKVKT
FVSRIIDTLD IGAAGTRVAV VNYASTVKIE FHLQTHSEKQ SLKKAVGRIT PLSTGTMSGL
AIQTAMEEVF TVEAGARGSS SNIPKVAIIV TDGRPQDQVN EVAARARASG IELYAVGVDR
ADKESLKMIA SKPLDEHVFY VETYGVIEKL SSRFQETFCA VDPCMLGTHR CQHVCVSDGD
GKHHCECSQG YSLNADKKTC SAIDKCALNT HGCEHKCVKD RTGSYHCECY EGYTLNEDRK
TCSAQNQCVS GTHGCQHVCV NDRAGSHHCE CYEGYTLNED NKTCSVRDQC ALGSHGCQHI
CVSDGPASYH CDCYTGFTLN QDRKTCSVIE EARRLISTED ACGCKATLAF QDKVSLYLQR
LNTKNILSGR FPASA
//
