ID L5KTT2_PTEAL Unreviewed; 1036 AA.
AC L5KTT2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Ataxin-2 {ECO:0000313|EMBL:ELK14341.1};
GN ORFNames=PAL_GLEAN10008871 {ECO:0000313|EMBL:ELK14341.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK14341.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the ataxin-2 family.
CC {ECO:0000256|ARBA:ARBA00007503}.
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DR EMBL; KB030576; ELK14341.1; -; Genomic_DNA.
DR AlphaFoldDB; L5KTT2; -.
DR STRING; 9402.L5KTT2; -.
DR eggNOG; KOG2375; Eukaryota.
DR InParanoid; L5KTT2; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd00600; Sm_like; 1.
DR InterPro; IPR009818; Ataxin-2_C.
DR InterPro; IPR045117; ATXN2-like.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR009604; LsmAD_domain.
DR InterPro; IPR047575; Sm.
DR InterPro; IPR025852; SM_dom_ATX.
DR PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR PANTHER; PTHR12854:SF11; ATAXIN-2; 1.
DR Pfam; PF06741; LsmAD; 1.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF14438; SM-ATX; 1.
DR SMART; SM01272; LsmAD; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 42..119
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
FT REGION 234..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..736
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 921..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..585
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 624..673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 674..691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 112942 MW; 5819F0F0E45DA007 CRC64;
MTDPCSGLLE QQSTEPYFRG RNNSKGLPQS TISFDGIYAN MRMVHILTSV VGSKCEVQVK
NGGIYEGVFK TYSPKCDLVL DAAHEKSTES SSGPKREEIM ESILFKCSDF VVVQFKDMDS
SYARRDAFTD SAISAKVNGE HKEKDLEPWD AGELTTSEEL EALENDVSNG WDPNDMFRYN
EENYGVVSTY DSSLSSYTVP LERDNSEEFL KREARANQLA EEIESSAQYK ARVALENDDR
SEEEKYTAVQ RNSSEREGHN INTRENKYIP PGQRNREVIS WGSGRQNSPR MGQPGSGSMP
SRSTSHTSDF NPNSGSDQRV VNGGKYFDQI CVPWPSPCPS PSSRPPSRYQ SGPNSLPPRA
ATPTRPPSRP PSRPSRPPSH PSAHGSPAPV STMPKRMSSE GPPRMSPKAQ RHPRNHRVSA
GRGSISSGLE FVSHTPPSEA AAPPTARTSP AGGTWSSVVS GVPRLSPKTH RPRSPRQNSI
GNTPSGPVLA SPQAGIIPTE AVAMPLPAAS PTPASPASNR AVTPSIEAKD PRLQDQRQNS
PAGNKENMKP NETSPSFSKA ENKGISPIVS EHRKQIDDLK KFKNDFRLQP SSTSESMDQL
LNKNREGEKS RDLIKDKIEP NAKDSFIENS SSNCTSGSSK PNSPSISPSI LSNTEHKRGP
EVTSQGVQTS SPGCKQEKDD KEEKKDAAEQ VRKSTLNPNA KEFNPRSFSQ PKPSTTPTSP
RPQAQPSPSM VGHQQPTPVY TQPVCFAPNM MYPVPVSPGV QPLYPIPMTP MPVNQAKTYR
AGKVPNMPQQ RQDQHHQSTM MHPASAAGPP IVATPPAYST QYVAYSPQQF PNQPLVQHVP
HYQSQHPHVY SPVIQGNARM MAPPAHAQPG LVSSSATQYG AHEQTHAMYA CPKLPYNKET
SPSFYFAIST GSLAQQYAHP NATLHPHTPH PQPSATPTGQ QQSQHGGNHP APSPVQHHQH
QAAQALHLAS PQQQSAIYHA GLAPTPPSMT PASNTQSPQN SFPTAQQTVF TIHPSHVQPA
YTNPPHMAHV PQVNQL
//
