ID   L5KX75_PTEAL            Unreviewed;       282 AA.
AC   L5KX75;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=Protein lin-7 homolog C {ECO:0000256|ARBA:ARBA00039649};
GN   ORFNames=PAL_GLEAN10018009 {ECO:0000313|EMBL:ELK15997.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK15997.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC       {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004202}.
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DR   EMBL; KB030484; ELK15997.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5KX75; -.
DR   STRING; 9402.L5KX75; -.
DR   eggNOG; KOG3550; Eukaryota.
DR   InParanoid; L5KX75; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 2.
DR   Gene3D; 1.10.287.650; L27 domain; 1.
DR   InterPro; IPR014775; L27_C.
DR   InterPro; IPR004172; L27_dom.
DR   InterPro; IPR036892; L27_dom_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR14063; PROTEIN LIN-7 HOMOLOG; 1.
DR   PANTHER; PTHR14063:SF5; PROTEIN LIN-7 HOMOLOG C; 1.
DR   Pfam; PF02828; L27; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00569; L27; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF101288; L27 domain; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51022; L27; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Cell junction {ECO:0000256|ARBA:ARBA00022427};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT   DOMAIN          75..130
FT                   /note="L27"
FT                   /evidence="ECO:0000259|PROSITE:PS51022"
FT   DOMAIN          158..260
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   282 AA;  31494 MW;  6C71D6E4C7A3A5C8 CRC64;
     MVQRTAHLQH LRSCTSSPEG LGETQTSLHL SRYWPDLALP ASSRPRPSPQ PLCRHFLWVC
     RQREKMAALG EPVRLERDIC RAIELLEKLQ RSGEVPPQKL QALQRVLQSE FCNAVREVYE
     HVYETVDISS SPEVRANATA KATVAAFAAS EGHSHPRVVE LPKTEEGLGF NIMGGKEQNS
     PIYISRIIPG GIADRHGGLK RGDQLLSVNG VSVEGEHHEK AVELLKAAQG KSVEGEHHEK
     AVELLKAAQG KVKLVVRYTP KVLEEMESRF EKMRSAKRRQ QT
//