ID L5KYT2_PTEAL Unreviewed; 3111 AA.
AC L5KYT2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 02-DEC-2020, entry version 24.
DE SubName: Full=Centromere protein F {ECO:0000313|EMBL:ELK16166.1};
GN ORFNames=PAL_GLEAN10017643 {ECO:0000313|EMBL:ELK16166.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK16166.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB030474; ELK16166.1; -; Genomic_DNA.
DR RefSeq; XP_006907786.1; XM_006907724.2.
DR RefSeq; XP_015441697.1; XM_015586211.1.
DR STRING; 9402.XP_006907786.1; -.
DR GeneID; 102885484; -.
DR KEGG; pale:102885484; -.
DR CTD; 1063; -.
DR eggNOG; ENOG502QVMD; Eukaryota.
DR InParanoid; L5KYT2; -.
DR OrthoDB; 205405at2759; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1891..2033
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2129..2268
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2311..2450
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2968..3012
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 211..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1659..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1715..1752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2888..3111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..445
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 718..752
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 831..872
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 898..956
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 961..995
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1056..1108
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1117..1171
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1195..1243
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1286..1320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1397..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1549..1601
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1626..1646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1792..1819
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1888..1908
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1916..2006
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2014..2083
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2105..2125
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2140..2216
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2224..2276
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2322..2374
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2378..2458
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2466..2493
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2498..2545
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2553..2608
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2616..2661
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2680..2714
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2737..2827
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2835..2862
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 471..490
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1666..1691
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1726..1740
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2888..2905
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2917..2953
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2954..2970
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2998..3012
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3035..3052
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3111 AA; 356668 MW; 73E87E56AD8699B2 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LDTLEAALQK QKQKVENEKT
EGTNLKRENQ SLMEICENLE KAKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQHYS GSKYEDLKEK YNKEVEERKR
LETEVKALQA KRASQAIPQN TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALQTPIRRD
FSASHFSGEQ DVTPSRSTLK VGKRDANSSF CDNSSNSHLL DQLKAQNQDL RSKISELELR
LQTQEKEMKS QVNKCQELQL HLEKAKVELN EKEKVLHKSR DELVRMTAQY DQASTKCTAL
EQKLKKLTED LSCQRQNAES AKCSLEQKAK EKEKAFQEEL SRQQRSFQAL DQEYTQMKAK
LTQELQQAKN THNVLQAELD KVTSVKYQLE KKWEEFKQKF CRTEQALQAS QTKEEELRRS
SEEMKKENGF LKSQSEQSAR EVCHLQEELK KTKQCLSQSQ NSVEEMRAKN TSQETMLRDL
QEKINQQENS LTLEKLKLAI ADLEKQRDCS QDLLKKREHH IEQLSEKLSK TERESKALLS
ALELKKKEYE ELKDEKTLFS HWKSENEQLL KQMESDKESL QSKINHLETC LKTQQIKSNE
YNERVRILEI ERENLNVEMR NLHNVIDSRN VEVETQKKAY IELQQKAESS DQKHKKEIEN
MSLKVSELTG QVEDLEHKLQ LLSSEITDKD QRYQDLHAEC ERLGALLKSK DSLVTNEALH
RSLLGFEQQS AIDNSFANIT GEQGSMPSER GGCHVEADRS PKNSAILQNR VVSLESSLES
QKQMNSDLQK QCEELVQIRG EIEENLVRAE QMHQSFVAET SQRISKLQED TSVHQNVLTE
TLVALENKER ELQLLKEKLE TEQAEIQELK KSNHLLQESL KELQLLSETL SLEKKETSSI
LSLTKKENEE LTHENRTLQE INATLNQEKM DLAQKSESFS QCVVEREKCI AELSNQYKQE
RLALLQRCEE TGNAFEDLSE KYKIVQEKSS KLECLLSECT SVCENRKNEL EQLKETFARE
HQALVTKLAF AEERNQTLKQ ELGAVQQDLR SEIADILNNS KREADGLKQE IVTLKEEHSK
MQKEVNALLQ ENEHLMKLME MKREHQNLES EPASDSVKAR ESAISKCHVQ LPMDLEVKDT
SLDSYNAQLE QLEAKTRSLE LKLQESEEEK ECLQHELETI RRQLETGTFQ RDAQSQEMSG
LKDCEKDTEE KYISVLHELS TSQSDNTQLQ CALQTAMNKL NELEKMCEML QVEKFELVSE
LNESRSECIT ATSKMAEDVE KLVHEVKLLN DENGLCQDEL VKEMPEDKPG EQQNEEKSLP
LNPLDDSNFH EHLTLSNKEV QMHFAELQEK FSSLQSEHKI LYDQHSHMSS KMSELRSYVD
TLKAENSVLS VSLRNSQGDL VKEGLLEPGE GHSLSLSFSR VADSLSFTSL GESSFYKDLL
EQAGEISFLN NLEGSVSSNQ STIEEVSYSS LEEEDLTKKA IPSSPKNSAE ELETLRQLYV
QSLKKLEEKM ESQEIMKNKE IKELEQLLSS ERKEFDCLRK QHLSENEQWQ QKLTSVTVEM
ESKLAAEKKQ TEHLSLELEV ARLQLQGLDL STRSLLGTDI EDDAQGGNDS CDKEESEEWT
SETRARTPKQ EVRQICENGV QQDLSLELEK RAETGAVTLA GERSREQSPD ASHGTPEEDE
AQGFSECTSA SSRSCPNASV PVDFLENQVA IQNLQLQVKE TTNENLRLLH IIEERDKNVE
ILLSEIKELD SKLNLQEVQL TTKTETCTEL GKIVEEFKKE KSDLIEKLES FSYDNPKVES
SEGLNSSLEM STGKLSHEVT EDNVSKTVDK WRERFLEMAN ELKSIKSEKS SVEHHAHSVE
ADLEVVQTEK LRLEKDNENK QQVITCLEEE LSVATCEKNQ LRGELDTLSK EYKELDLMSE
KMKEKIQELE SHREECQRHI GVVEAEVKDK TQLLQTLSSD VSELLKDKTH LQEQMQSLEK
DSQALSSVKS ELESQIGQLH EEKESLVRES ESLQTKLHDL EHEKLTVAKA LEAALTEKGE
VAVRLSSTQE EVRHLRDGIE KLRVRIEADE KKQLHVLEKL KDSERKSDSL QDKVENLERE
LQMSEENQEM VILDAENSKA EVESLKTQVE LMTERLKALE LDLVTIKSEK GNLMKQLLEK
QGQLSELDVL LSSFKNLLEE KEQEKIQMKG ESEAAEEMLQ TELKELNEAV AALCDDQEAG
RDKEQSLGSP VQVMHQLRSS ITKLKVHLEA DGKKQLHALG KLKESEHQAD VLKDRVENLE
RELEISRKNQ ERAILEAENS KAEVETLKAR IEEMAPNLRE LESDLVNIRT EKENLTKELQ
KEQGRVSELE ILNSSFENRL QEKEQEKVQM KEESKIAVDR LQTQLKELNE KVTALCDDQE
TWKVREQNLS GQVDRLELEK AQLLQSLDET KSNYIILQSS VNGLIQELED EKQKLEKKNG
EISELKNQVQ DQEQLVSKLS QAEGEQQVWE KHKGELENLT VELEQKIQGL QSKNDTLQDT
LEALQNSYKD LEKELELTEM QKTSFVEKIN AMTSKETELQ REIHDMVQKT TELKEEFSRE
KNKLTEELNL MVEEIKSSKG QLEQFMLENS ELKKSLDCVH KDQTEKQEKM REEIAEYQLQ
LQEAEKKHQA LLLDTNKQHE MEIQTYREKL TSKEECLSSQ KVELDLLKSS KEELNNSLKA
TTELLEELRK TKMDNLKHVN QLKKENERAQ GKIKLLIKSC KQLEEEKEML QKELSHLEEA
AQEKQKTGTV VDASVDELMT EVKELKETLE EKSKEADEYL DKYCSLLISH EKLERAKEML
ETQVARLSSR PSKLNLQSSP SLNSVVPGPS PVPSVPEKKL SSGQNKGSGK RQRSSGIREN
GGGTASSTPE TFSKKSKKVV KSGIHPTEDA EDTEFEPEGL PEVVKKGFAD IPTGKTSPYV
LRRTTMATRT SPRLAAQKLA LSPLSLHKEN HAETSKPTAG GSRSQKVKAL QRSPADTGTA
LWEPSARSLP AGHLPAQSSA DSPYKGLRAK RGRLAPSPEA GPESNENCRV Q
//
