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Database: UniProt
Entry: L5KYT2_PTEAL
LinkDB: L5KYT2_PTEAL
Original site: L5KYT2_PTEAL 
ID   L5KYT2_PTEAL            Unreviewed;      3111 AA.
AC   L5KYT2;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   02-DEC-2020, entry version 24.
DE   SubName: Full=Centromere protein F {ECO:0000313|EMBL:ELK16166.1};
GN   ORFNames=PAL_GLEAN10017643 {ECO:0000313|EMBL:ELK16166.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK16166.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB030474; ELK16166.1; -; Genomic_DNA.
DR   RefSeq; XP_006907786.1; XM_006907724.2.
DR   RefSeq; XP_015441697.1; XM_015586211.1.
DR   STRING; 9402.XP_006907786.1; -.
DR   GeneID; 102885484; -.
DR   KEGG; pale:102885484; -.
DR   CTD; 1063; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   InParanoid; L5KYT2; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1891..2033
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2129..2268
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2311..2450
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2968..3012
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          211..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          471..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1659..1694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1715..1752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2888..3111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..445
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          718..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          831..872
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          898..956
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          961..995
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1056..1108
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1117..1171
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1195..1243
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1286..1320
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1397..1417
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1549..1601
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1626..1646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1792..1819
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1888..1908
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1916..2006
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2014..2083
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2105..2125
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2140..2216
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2224..2276
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2322..2374
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2378..2458
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2466..2493
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2498..2545
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2553..2608
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2616..2661
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2680..2714
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2737..2827
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2835..2862
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        471..490
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1666..1691
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1726..1740
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2888..2905
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2917..2953
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2954..2970
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2998..3012
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3035..3052
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3111 AA;  356668 MW;  73E87E56AD8699B2 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LDTLEAALQK QKQKVENEKT
     EGTNLKRENQ SLMEICENLE KAKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQHYS GSKYEDLKEK YNKEVEERKR
     LETEVKALQA KRASQAIPQN TMNHRDIARH QASSSVFSWQ QEKTPSRLSS SALQTPIRRD
     FSASHFSGEQ DVTPSRSTLK VGKRDANSSF CDNSSNSHLL DQLKAQNQDL RSKISELELR
     LQTQEKEMKS QVNKCQELQL HLEKAKVELN EKEKVLHKSR DELVRMTAQY DQASTKCTAL
     EQKLKKLTED LSCQRQNAES AKCSLEQKAK EKEKAFQEEL SRQQRSFQAL DQEYTQMKAK
     LTQELQQAKN THNVLQAELD KVTSVKYQLE KKWEEFKQKF CRTEQALQAS QTKEEELRRS
     SEEMKKENGF LKSQSEQSAR EVCHLQEELK KTKQCLSQSQ NSVEEMRAKN TSQETMLRDL
     QEKINQQENS LTLEKLKLAI ADLEKQRDCS QDLLKKREHH IEQLSEKLSK TERESKALLS
     ALELKKKEYE ELKDEKTLFS HWKSENEQLL KQMESDKESL QSKINHLETC LKTQQIKSNE
     YNERVRILEI ERENLNVEMR NLHNVIDSRN VEVETQKKAY IELQQKAESS DQKHKKEIEN
     MSLKVSELTG QVEDLEHKLQ LLSSEITDKD QRYQDLHAEC ERLGALLKSK DSLVTNEALH
     RSLLGFEQQS AIDNSFANIT GEQGSMPSER GGCHVEADRS PKNSAILQNR VVSLESSLES
     QKQMNSDLQK QCEELVQIRG EIEENLVRAE QMHQSFVAET SQRISKLQED TSVHQNVLTE
     TLVALENKER ELQLLKEKLE TEQAEIQELK KSNHLLQESL KELQLLSETL SLEKKETSSI
     LSLTKKENEE LTHENRTLQE INATLNQEKM DLAQKSESFS QCVVEREKCI AELSNQYKQE
     RLALLQRCEE TGNAFEDLSE KYKIVQEKSS KLECLLSECT SVCENRKNEL EQLKETFARE
     HQALVTKLAF AEERNQTLKQ ELGAVQQDLR SEIADILNNS KREADGLKQE IVTLKEEHSK
     MQKEVNALLQ ENEHLMKLME MKREHQNLES EPASDSVKAR ESAISKCHVQ LPMDLEVKDT
     SLDSYNAQLE QLEAKTRSLE LKLQESEEEK ECLQHELETI RRQLETGTFQ RDAQSQEMSG
     LKDCEKDTEE KYISVLHELS TSQSDNTQLQ CALQTAMNKL NELEKMCEML QVEKFELVSE
     LNESRSECIT ATSKMAEDVE KLVHEVKLLN DENGLCQDEL VKEMPEDKPG EQQNEEKSLP
     LNPLDDSNFH EHLTLSNKEV QMHFAELQEK FSSLQSEHKI LYDQHSHMSS KMSELRSYVD
     TLKAENSVLS VSLRNSQGDL VKEGLLEPGE GHSLSLSFSR VADSLSFTSL GESSFYKDLL
     EQAGEISFLN NLEGSVSSNQ STIEEVSYSS LEEEDLTKKA IPSSPKNSAE ELETLRQLYV
     QSLKKLEEKM ESQEIMKNKE IKELEQLLSS ERKEFDCLRK QHLSENEQWQ QKLTSVTVEM
     ESKLAAEKKQ TEHLSLELEV ARLQLQGLDL STRSLLGTDI EDDAQGGNDS CDKEESEEWT
     SETRARTPKQ EVRQICENGV QQDLSLELEK RAETGAVTLA GERSREQSPD ASHGTPEEDE
     AQGFSECTSA SSRSCPNASV PVDFLENQVA IQNLQLQVKE TTNENLRLLH IIEERDKNVE
     ILLSEIKELD SKLNLQEVQL TTKTETCTEL GKIVEEFKKE KSDLIEKLES FSYDNPKVES
     SEGLNSSLEM STGKLSHEVT EDNVSKTVDK WRERFLEMAN ELKSIKSEKS SVEHHAHSVE
     ADLEVVQTEK LRLEKDNENK QQVITCLEEE LSVATCEKNQ LRGELDTLSK EYKELDLMSE
     KMKEKIQELE SHREECQRHI GVVEAEVKDK TQLLQTLSSD VSELLKDKTH LQEQMQSLEK
     DSQALSSVKS ELESQIGQLH EEKESLVRES ESLQTKLHDL EHEKLTVAKA LEAALTEKGE
     VAVRLSSTQE EVRHLRDGIE KLRVRIEADE KKQLHVLEKL KDSERKSDSL QDKVENLERE
     LQMSEENQEM VILDAENSKA EVESLKTQVE LMTERLKALE LDLVTIKSEK GNLMKQLLEK
     QGQLSELDVL LSSFKNLLEE KEQEKIQMKG ESEAAEEMLQ TELKELNEAV AALCDDQEAG
     RDKEQSLGSP VQVMHQLRSS ITKLKVHLEA DGKKQLHALG KLKESEHQAD VLKDRVENLE
     RELEISRKNQ ERAILEAENS KAEVETLKAR IEEMAPNLRE LESDLVNIRT EKENLTKELQ
     KEQGRVSELE ILNSSFENRL QEKEQEKVQM KEESKIAVDR LQTQLKELNE KVTALCDDQE
     TWKVREQNLS GQVDRLELEK AQLLQSLDET KSNYIILQSS VNGLIQELED EKQKLEKKNG
     EISELKNQVQ DQEQLVSKLS QAEGEQQVWE KHKGELENLT VELEQKIQGL QSKNDTLQDT
     LEALQNSYKD LEKELELTEM QKTSFVEKIN AMTSKETELQ REIHDMVQKT TELKEEFSRE
     KNKLTEELNL MVEEIKSSKG QLEQFMLENS ELKKSLDCVH KDQTEKQEKM REEIAEYQLQ
     LQEAEKKHQA LLLDTNKQHE MEIQTYREKL TSKEECLSSQ KVELDLLKSS KEELNNSLKA
     TTELLEELRK TKMDNLKHVN QLKKENERAQ GKIKLLIKSC KQLEEEKEML QKELSHLEEA
     AQEKQKTGTV VDASVDELMT EVKELKETLE EKSKEADEYL DKYCSLLISH EKLERAKEML
     ETQVARLSSR PSKLNLQSSP SLNSVVPGPS PVPSVPEKKL SSGQNKGSGK RQRSSGIREN
     GGGTASSTPE TFSKKSKKVV KSGIHPTEDA EDTEFEPEGL PEVVKKGFAD IPTGKTSPYV
     LRRTTMATRT SPRLAAQKLA LSPLSLHKEN HAETSKPTAG GSRSQKVKAL QRSPADTGTA
     LWEPSARSLP AGHLPAQSSA DSPYKGLRAK RGRLAPSPEA GPESNENCRV Q
//
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