ID   L5L191_PTEAL            Unreviewed;       256 AA.
AC   L5L191;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN   ORFNames=PAL_GLEAN10014099 {ECO:0000313|EMBL:ELK16818.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK16818.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB030429; ELK16818.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5L191; -.
DR   STRING; 9402.L5L191; -.
DR   eggNOG; KOG4628; Eukaryota.
DR   InParanoid; L5L191; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd02123; PA_C_RZF_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR044744; ZNRF4/RNF13/RNF167_PA.
DR   PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02225; PA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          55..145
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
SQ   SEQUENCE   256 AA;  28589 MW;  13B035BDF1D31A85 CRC64;
     MNPSTSLLPV VVATMLWGAA PIWGLIRATS DHNVSMDFAD LPALFGSALS REGLQGFLVE
     AHPANACSPI APPPPALVSG PVFIALLRRY DCSFDHKVLN VQKAGYGAAV VHNVNSNKLL
     NMMWSSVEIR QQIRIPSVFI GARSSEYLRA LFLYHKGAQV LLLPDNSFIL IYYCLIPFTG
     IVGLLILTGA VMLLRCIQHQ KQLQRNRLTQ QQLKLIPTHD YQKGDQYDVC VICLDEYEDG
     DKLRAYEMDF LELFLN
//