ID L5L1T9_PTEAL Unreviewed; 287 AA.
AC L5L1T9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=F-box/SPRY domain-containing protein 1 {ECO:0000256|ARBA:ARBA00016614};
DE AltName: Full=F-box only protein 45 {ECO:0000256|ARBA:ARBA00029979};
GN ORFNames=PAL_GLEAN10007372 {ECO:0000313|EMBL:ELK17602.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK17602.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the FBXO45/Fsn family.
CC {ECO:0000256|ARBA:ARBA00007328}.
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DR EMBL; KB030403; ELK17602.1; -; Genomic_DNA.
DR RefSeq; XP_006906215.1; XM_006906153.2.
DR AlphaFoldDB; L5L1T9; -.
DR STRING; 9402.L5L1T9; -.
DR GeneID; 102886056; -.
DR KEGG; pale:102886056; -.
DR CTD; 200933; -.
DR eggNOG; KOG3953; Eukaryota.
DR InParanoid; L5L1T9; -.
DR OrthoDB; 65989at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd22111; F-box_FBXO45; 1.
DR CDD; cd12907; SPRY_Fbox; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035784; SPRY_FBXO45.
DR PANTHER; PTHR12245:SF7; F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 34..83
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 93..285
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 287 AA; 30726 MW; CB0B9CBA35748A48 CRC64;
MAAPAPGAGA ASGGAGCSSG GGGGASSGSG SGSAGAGGRL PSRVLELVFS YLELSELRSC
ALVCKHWYRC LHGDENSEVW RSLCARSLAE EALRTDILCN LPSYKAKVRA FQHAFSTNDC
SRNVYIKKNG FTLHRNPIAQ STDGARTKIG FSEGRHAWEV WWEGPLGTVA VIGIATKRAP
MQCQGYVALL GSDDQSWGWN LVDNNLLHNG EVNGSFPQCN NAPKYQIGER IRVILDMEDK
TLAFERGYEF LGVAFRGLPK ACLYPAVSAV YGNTEVTLVY LGKPLDG
//
