ID L5L3X9_PTEAL Unreviewed; 719 AA.
AC L5L3X9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ATP-dependent RNA helicase DQX1 {ECO:0000313|EMBL:ELK18409.1};
GN ORFNames=PAL_GLEAN10008541 {ECO:0000313|EMBL:ELK18409.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK18409.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB030330; ELK18409.1; -; Genomic_DNA.
DR STRING; 9402.L5L3X9; -.
DR eggNOG; KOG0925; Eukaryota.
DR InParanoid; L5L3X9; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF108; ATP-DEPENDENT RNA HELICASE DQX1; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELK18409.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELK18409.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ELK18409.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806,
KW ECO:0000313|EMBL:ELK18409.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 33..234
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|SMART:SM00487"
FT DOMAIN 443..532
FT /note="Helicase-associated"
FT /evidence="ECO:0000259|SMART:SM00847"
FT REGION 692..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 719 AA; 79393 MW; F6E8AB884DDB72B8 CRC64;
MASQLLRLAE ESGLSPGESE LAVNPFDGLP FSSRYYELLE QRRALPIWAA RFIFLEQLES
SPSGVVLVSG EPGSGKSTQI PQWCAEFVLA RGFQKGRITV TQPYPLAALS LALRIADEMD
LIVGHEIGYS IPQEDCTGPH TLLRFCWDRL LLQELASTRG TGAWDVLVLD EVQERSVASD
LLQGLLRNAK LGNLPDDPRV VVVTDPALEP KLQAFWGNPP IVHVPRGPGR YPILIYRDTV
PTDRVEAACQ AVLELCQKEA PGDVLVYLPS EEEITLCCES LSREVGTLAL QGPPPRVLPL
HPGHGQAVQA VYEDINSGAR KVVVTHWLAD FSFSLPSIRH VIDSGLELRS VYNPQIRAES
QVLRPISKCQ AEARQLRARG APPGSCLCLY PKSFRELEAP PLPQPRVCEE NLSPLVLLLK
RRQIAEPGKC QFLDWPAPEA LMQALEDLDY LAALDDDGDL SDLGVILSEF PLPPELAKAL
LASCEFDCVD EMLTLAAMLT AAPGFTHPPL CTKEAALRRA LEHVDGDHSS LIQVYEGFIQ
SGTDKAWCQA RGLNWAALCQ AQKLRGELLE LMQRIELPLS QPAFGSEKNR RDLQKALLSG
YFLXVAQDTD GTGNYLLLTH KHVAQLSPYC CYRSRRAPAR PPPWVLYHNF SISKDNCLSI
VSEIQPQMLV ELAPPYFLSN LPPSESRDFL NQLREEMAAS STESESSSTQ ELGDACVLQ
//
