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Database: UniProt
Entry: L5LAK7_MYODS
LinkDB: L5LAK7_MYODS
Original site: L5LAK7_MYODS 
ID   L5LAK7_MYODS            Unreviewed;       395 AA.
AC   L5LAK7;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   08-MAY-2019, entry version 33.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 11 {ECO:0000313|EMBL:ELK23232.1};
GN   ORFNames=MDA_GLEAN10001051 {ECO:0000313|EMBL:ELK23232.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
OC   Vespertilionidae; Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK23232.1};
RN   [1] {ECO:0000313|EMBL:ELK23232.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Spleen {ECO:0000313|EMBL:ELK23232.1};
RA   Zhang G., Cowled C., Wang L.;
RT   "Comparative analysis of bat genomes provides insight into the
RT   evolution of flight and immunity.";
RL   Science 0:0-0(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KB113777; ELK23232.1; -; Genomic_DNA.
DR   RefSeq; XP_006773101.1; XM_006773038.2.
DR   STRING; 225400.XP_006773101.1; -.
DR   GeneID; 102760388; -.
DR   KEGG; myd:102760388; -.
DR   CTD; 3767; -.
DR   KO; K05004; -.
DR   OrthoDB; 956263at2759; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003279; K_chnl_inward-rec_Kir6.2.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF44; PTHR11767:SF44; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01332; KIR62CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:ELK23232.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     72     93       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    149    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       36    178       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      186    358       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        165    165       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   395 AA;  44102 MW;  74508312AC2477C1 CRC64;
     MLSRKGIIPE EYVLTRLAED PAEPRYRARE RRARFVSKKG NCNVAHKNIR EQGRFLQDVF
     TTLVDLKWPH TLLIFTMSFL CSWLLFAMVW WLIAFAHGDL APVDLAPGED AMVPCVTSIH
     SFSSAFLFSI EVQVTIGFGG RMVTEECPLA ILILIVQNIV GLMINAIMLG CIFMKTAQAH
     RRAETLIFSK HAVIALRQGR LCFMLRVGDL RKSMIISATI HMQVVRKTTS PEGEVVPLHQ
     VDIPMENGVG GNSIFLVAPL IIYHIIDANS PLYDLAPSDL HHHQDLEIIV ILEGVVETTG
     ITTQARTSYL ADEILWGQRF VPIVSEEDGR YAVDYSKFGN TIKVPTPLCT ARQLDEDRSL
     LDALTLATAR GPLRKRSVAI AKAKPRFSIS PDSLS
//
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