ID L5LBP8_MYODS Unreviewed; 245 AA.
AC L5LBP8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Phosducin {ECO:0000256|ARBA:ARBA00040013};
GN ORFNames=MDA_GLEAN10017474 {ECO:0000313|EMBL:ELK23301.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK23301.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, photoreceptor outer
CC segment {ECO:0000256|ARBA:ARBA00004504}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}. Photoreceptor inner segment
CC {ECO:0000256|ARBA:ARBA00004437}.
CC -!- SIMILARITY: Belongs to the phosducin family.
CC {ECO:0000256|ARBA:ARBA00009686}.
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DR EMBL; KB113703; ELK23301.1; -; Genomic_DNA.
DR RefSeq; XP_006773004.1; XM_006772941.2.
DR RefSeq; XP_015425436.1; XM_015569950.1.
DR RefSeq; XP_015425437.1; XM_015569951.1.
DR AlphaFoldDB; L5LBP8; -.
DR GeneID; 102775473; -.
DR KEGG; myd:102775473; -.
DR CTD; 5132; -.
DR eggNOG; KOG3171; Eukaryota.
DR OrthoDB; 2912029at2759; -.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR CDD; cd02987; Phd_like_Phd; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 1.10.168.10; Phosducin, domain 2; 2.
DR InterPro; IPR001200; Phosducin.
DR InterPro; IPR023196; Phosducin_N_dom_sf.
DR InterPro; IPR024253; Phosducin_thioredoxin-like_dom.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR46052:SF3; PHOSDUCIN; 1.
DR PANTHER; PTHR46052; PHOSDUCIN-LIKE PROTEIN; 1.
DR Pfam; PF02114; Phosducin; 1.
DR PRINTS; PR00677; PHOSDUCIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023069};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00023305};
KW Vision {ECO:0000256|ARBA:ARBA00023305}.
FT DOMAIN 2..241
FT /note="Phosducin thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF02114"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 36..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 28384 MW; B80CA5B8E9035D0A CRC64;
MEEAKNPSLE EDFEGQVTHT GPKGVIHDWR KFKLESEDND SVPPSKKEIL RQMSSPQSRD
DRDSKERFSR KMSIQEYELI HQDKEDETCL RKYRRQCMQD MHQKLSFGPR YGFVYELETG
EQFLETIEKE KKITTIVVHI YEEGIKGCDA LNSSLTCLAA EYPMVKFCKI KASHTGAEDR
FSSDVLPTLL VYKGGELISN FISVAEQFAE EFFAGDVESF LNEYGLLPER EIHALEQTNM
EEDIE
//