ID L5LCV5_MYODS Unreviewed; 347 AA.
AC L5LCV5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|EMBL:ELK23716.1};
GN ORFNames=MDA_GLEAN10012463 {ECO:0000313|EMBL:ELK23716.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK23716.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; KB113185; ELK23716.1; -; Genomic_DNA.
DR AlphaFoldDB; L5LCV5; -.
DR eggNOG; KOG1292; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR11119:SF21; SOLUTE CARRIER FAMILY 23 MEMBER 1; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..347
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003970180"
FT TRANSMEM 50..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 322..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 36961 MW; E3048D71A31A3477 CRC64;
MTVWLLCYIL TLTDVLPTDP TAYGFQARTD ARGDIMATAP WIRIPYPCQW GLPTVTAAAV
LGMFSATLAG IIESIGDYYA CARLAGAPPP PVHAINRGIF TEGICCIIAG LLGTGNGSTS
SSPNIGVLGI TKVGSRRVVQ YGAGIMLVLG TIGKFTALFA SLPDPILGGM FCTLFGMITA
VGLSNLQFVD MNSSRNLFVL GFSMFFGLTL PNYLESNPGA INTGAPTCLN VTAGIPEVDQ
ILTVLLTTEM FVGGCLAFLL DNTVPGSPEE RGLVQWKAGA HANSEMSTSL KSYDFPFGMN
MIKRIAFLKY IPICPVFKGF SSRSKDQRPV PEDISENRET GPVCTKI
//
