ID L5LER6_MYODS Unreviewed; 927 AA.
AC L5LER6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=General transcription factor II-I repeat domain-containing protein 2 {ECO:0000313|EMBL:ELK24834.1};
GN ORFNames=MDA_GLEAN10017260 {ECO:0000313|EMBL:ELK24834.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK24834.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB112378; ELK24834.1; -; Genomic_DNA.
DR RefSeq; XP_006770918.1; XM_006770855.2.
DR AlphaFoldDB; L5LER6; -.
DR GeneID; 102775069; -.
DR KEGG; myd:102775069; -.
DR CTD; 389524; -.
DR eggNOG; ENOG502QQSX; Eukaryota.
DR OrthoDB; 3145784at2759; -.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 3.90.1460.10; GTF2I-like; 2.
DR InterPro; IPR004212; GTF2I.
DR InterPro; IPR036647; GTF2I-like_rpt_sf.
DR InterPro; IPR042224; GTF2IRD2.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR040647; SPIN-DOC_Znf-C2H2.
DR PANTHER; PTHR47831; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR47831:SF1; GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED; 1.
DR Pfam; PF02946; GTF2I; 2.
DR Pfam; PF18658; zf-C2H2_12; 1.
DR SUPFAM; SSF117773; GTF2I-like repeat; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51139; GTF2I; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 407..468
FT /note="SPIN-DOC-like zinc-finger"
FT /evidence="ECO:0000259|Pfam:PF18658"
SQ SEQUENCE 927 AA; 104662 MW; 798FFDE3770FCA4E CRC64;
MAQVAMSSLP VENEASSESR MVVTFLMSTL DSMCKELAKS RVEVACIAMY EAEVFVVGTE
KGRAFASARM DLQMDFAKYC AAEGLLETKP LSPVQGMKLN SGETEILRKA VEDYFCLCYG
KALGTTAMVP VPYEKMLRDQ AAVVVQGLPE GVAFQHPENY DLETLKWILE NKAGISFIIN
RPFLGPADPQ GGPGVVTDAE RAMSLSSESG GSIHVKTEPM EDSGISLKAA AASVKKESED
PNYYQYNMQE SHHSSAINEV IEMELPMEGN TNPSNTTSSA AGVEDLNIVQ VTIPDNEKER
LSSMEKIKQL REQVNDLFSR KFGEAIGVDF PVKVPYRKIT FNPGCVVIDG MPPGVVFKAP
GYLEISSLRR ILDAAEFIKF TVIRPLPGLE FNNVGKRKID LEGRVFQEKW ERAYFFVEVQ
NIPTCLICKQ SMSVSKEYNL RRHYQTNHSK HYDQYTEKMR DEKLHELKKG LRKYLFGSSE
TVCPEQKELF ANASPNDNAA MQAAEDVTGN LWEKLREKIR SFVAYSIAID EITDINNITQ
LAIFIRGVDE SFDVSEELLD TVPMTGTKSG NEVFLRVEKS LKKFNIDWSK LVSVASTGTP
AMVDANNGLV TKLKSKVATV CKGSDLKSVC CIIHPESLCA QRLKMDHVMN VVVNSVNWIC
SRGLNHSEFT TLLYELDCQY GSLLYYTEIK WLSRGLVLKR FFESLEEIDS FMSSRGKPLP
QLSSQDWVRD LAFLVDMTMH LNTLSLSLQG HSQIVTQMYD LIRAFLAKLC LWETHLARNN
LAHFPTLKSV SRNESDSLNY IPKIVELKTE FQKRLSDFKL YESELTLFSS PFSVKIESIH
EALQMEVIEL QCNMVLKTKY DKVGIPEFYK HLWSSYPRYK SHCAKILSMF GSTYICEQLF
SIMKLSKTKY CSELKDSQWD SVLHIST
//
