ID   L5LIV1_MYODS            Unreviewed;       657 AA.
AC   L5LIV1;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=ETS-related transcription factor Elf-4 {ECO:0000313|EMBL:ELK25553.1};
GN   ORFNames=MDA_GLEAN10010869 {ECO:0000313|EMBL:ELK25553.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK25553.1, ECO:0000313|Proteomes:UP000010556};
RN   [1] {ECO:0000313|Proteomes:UP000010556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC       ECO:0000256|RuleBase:RU004019}.
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DR   EMBL; KB111736; ELK25553.1; -; Genomic_DNA.
DR   RefSeq; XP_006769928.1; XM_006769865.2.
DR   AlphaFoldDB; L5LIV1; -.
DR   GeneID; 102753327; -.
DR   KEGG; myd:102753327; -.
DR   CTD; 2000; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   OrthoDB; 4245771at2759; -.
DR   Proteomes; UP000010556; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR046328; ETS_fam.
DR   InterPro; IPR022084; TF_Elf_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849; ETS; 1.
DR   PANTHER; PTHR11849:SF170; ETS-RELATED TRANSCRIPTION FACTOR ELF-4; 1.
DR   Pfam; PF12310; Elf-1_N; 1.
DR   Pfam; PF00178; Ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW   Nucleus {ECO:0000256|RuleBase:RU004019};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT   DOMAIN          208..290
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          117..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..171
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        311..337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   657 AA;  70467 MW;  4FCB54DE73269B8C CRC64;
     MAITLQPSDL IFEFASNGMD DIHQLEDPSV FPAVIVEQVP YPELLHLYSG LELEDGHNGI
     ITDRTLCMTQ DQILEGSFML ADENEATSQT MSTTEVLLNV ESPNNILDEK QIFSTSELLP
     DSDPAPATTL PNYLFPVSEP NAMNSAGDTG DQEGHSLEEQ VSKEESAKKT GKPKKRIRKT
     KGNRSTSPVT DPSIPIRKKS KDGKGNTIYL WEFLLALLQD RNTCPKYIKW TQREKGIFKL
     VDSKAVSKLW GKQKNKPDMN YETMGRALRY YYQRGILAKV EGQRLVYQFK EMPKDLVVIE
     DEDEKSEVAE ASPKASTSTS TTRRASSRVS SRAAPQGKSS PPWEKPKVQH VGLQSSASLE
     LGLSPDEEIP TTSTVLVSPP EGQAKLTKAV SASSVPGNIH LGVAPVGSAS ALTLQTIPLT
     TVLTNGPPVS TTTSTQLVLQ SVPPASTFKD TFTLQASFPL NASFQENQVA APGTPLILSG
     LPQLLAGANR STNPTAASVT GAGVAGPSSQ PPGTVIAAFI RTSSATATPG VKDGSLRPNS
     YVQGMVTGAP MEGLLVPEET LRELLRDQAH LQPLPAHVVS RGSHNLSLLG NQTFSPPSRP
     TVGLTPVAEL ELSSSSGSLF MAEPSVTTSG TLLTRSPTPA PFPFNPTSLI KMEPHNI
//