ID   L5LJD1_MYODS            Unreviewed;      1015 AA.
AC   L5LJD1;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 3 {ECO:0000313|EMBL:ELK26110.1};
GN   ORFNames=MDA_GLEAN10006838 {ECO:0000313|EMBL:ELK26110.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK26110.1, ECO:0000313|Proteomes:UP000010556};
RN   [1] {ECO:0000313|Proteomes:UP000010556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB111258; ELK26110.1; -; Genomic_DNA.
DR   eggNOG; KOG3533; Eukaryota.
DR   Proteomes; UP000010556; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   Gene3D; 2.80.10.50; -; 3.
DR   Gene3D; 1.25.10.30; IP3 receptor type 1 binding core, RIH domain; 1.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_IP3_receptor.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR45816:SF1; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; 1.
DR   PANTHER; PTHR45816; MIR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   SMART; SM00472; MIR; 2.
DR   SUPFAM; SSF100909; IP3 receptor type 1 binding core, domain 2; 2.
DR   SUPFAM; SSF82109; MIR domain; 1.
DR   PROSITE; PS50919; MIR; 1.
PE   4: Predicted;
KW   Receptor {ECO:0000313|EMBL:ELK26110.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          139..195
FT                   /note="MIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50919"
FT   REGION          226..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          890..920
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        890..914
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1015 AA;  114925 MW;  814F0F7D3BB724CF CRC64;
     MEQKQNDTEN KKVHGDVVKL VDDRCVVEPA AGDLDNPPKK FRDCLFKVCP MNRYSAQKQY
     WKAKQTKQDK EKISDVVLLQ KLQVNSVNCN TSWKINLFMQ FRDHLDEGVK GVVVGDKVIL
     NPVNAGQPLH ASNYELSDNA GCKEGDVVRL FHAEQEKFLT CDEYKGKLQV FLRTTLRQSA
     TSATSSNALW EVEVVHHDPC RGGAGHWNGL YRFKHLATGN YLAAEENPSY KGDASDPKAA
     GAGAQGRPGR RNAGEKIKYR LVAVPHGNDI ASLFELDPTT LQKTDSFVPR LLGTCPTKED
     KEAFAIVSVP VSEIRDLDFA NDASSMLASA VEKLNEGFIS QNDRRFVIQL LEDLVFFVSD
     VPNNGQNVLD IMVTKPNRER QKLMREQNIL KQIFGILKAP FRDKGGEGPL VRLEELSDQK
     NAPYQHMFRL CYRVLRHSQE DYRKNQELIC KCVLDPKNSD ILIQTELRPV KEMAQAHEYQ
     LKLFARMCLD RQYLAIHEIS QQLGVDLIFL CMADEMLPFD LRASFCHLML HVHVDRDPQE
     LVTPVKFARL WTEIPTAITI KDYDSNLNAA RDDKKNKFAS TMEFVEDYLN NVVGEAVPFA
     NEDKNKLTFE AXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXGTLLS IIDCVQGPPA
     MLQAYEDSAG KNVRRSIQGV GSLVVERTNN LWVIPLSLPA EAGAAEPLDR SKFEENEDIV
     VMETKLKILE ILQFILNVRL DYRISYLLSV FKKEFVEVFP MQDSGADGTA PAFDSTTANM
     NLDRIGEQAE AMFGVGKTSS MLEVDDEGGR TFLRVLIHLT MHDYPPLVSG ALQLLFKHFS
     QRQEAMHTFK QVQLLISAQD VENYKVIKAE LDRLRTMVEK SELWVDKKGS GKGEEVEAGT
     AKDKKERPTD EEGFLPPPGE KSSENYQIVK GILERLNKMC GVGEQMRKKQ QRLLKNMDAH
     KVMLDLLQIP YDKGDAKMME ILRYTHQFLQ KFCAGNPGNQ ALLHKHLHLF LRSDL
//