ID L5LTU8_MYODS Unreviewed; 534 AA.
AC L5LTU8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Lymphocyte cytosolic protein 2 {ECO:0000313|EMBL:ELK28898.1};
GN ORFNames=MDA_GLEAN10021381 {ECO:0000313|EMBL:ELK28898.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK28898.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB108645; ELK28898.1; -; Genomic_DNA.
DR RefSeq; XP_006765443.1; XM_006765380.2.
DR AlphaFoldDB; L5LTU8; -.
DR GeneID; 102757528; -.
DR KEGG; myd:102757528; -.
DR CTD; 3937; -.
DR eggNOG; ENOG502QV3T; Eukaryota.
DR OrthoDB; 5351675at2759; -.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR CDD; cd09522; SAM_SLP76; 1.
DR CDD; cd09929; SH2_BLNK_SLP-76; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR14098:SF1; LYMPHOCYTE CYTOSOLIC PROTEIN 2; 1.
DR PANTHER; PTHR14098; SH2 DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF07647; SAM_2; 1.
DR Pfam; PF00017; SH2; 1.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 423..531
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 79..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..150
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..216
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..328
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 60013 MW; 6ECE5A3237C5F17B CRC64;
MALRNVPFRS EVLAWDPDSL ADYFRKLNYK DCEKAVRKHH IDGPRFLNLT ENDIQKFPKL
RVPILSKLSQ EINKNEERRS IFAPRKPQVH RFPEEIESHE EENGGWSSFE EDDYESPNDD
QDAEDDGDYE SPNEEDQAPL EDDADYEPPP SNDEEALQNS ILPAKPFSNS NSMYIDRPLS
GKSPQQPPVP PQRPMAALPP PPAGRSHTPL PTPQPNHEEP SRSRTPKTAK LPAPSIDRST
KPTLDRSLAP FDREPLTLGK KPVLSDKPPT PAGRPLGDHL PKIPKPPLPL TAERHDRSSP
LPGKKPPVPK HARAPDRREN DEDDVHQRPL PQPALLPMSS NTFPSRSNKP SPKPSLPSTH
NFGAFSESSS SFPQSASLPP CFSQGPGNRP PLRSEGRNFS LPVPTKPRPP SPGEEENPLS
EEWYVSYITR PEAEAALRRI NQDGTFLVRD SSKKTPSNPY VLMVLYKDKV YNVQIRYVEE
SHVYMLGTGL RGKEDFLSVS DIIDYFRKMP LLLIDGKNRG SRYQCTLTHS AGCP
//
