ID L5LTW2_MYODS Unreviewed; 910 AA.
AC L5LTW2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=SH3 and PX domain-containing protein 2B {ECO:0000313|EMBL:ELK28913.1};
GN ORFNames=MDA_GLEAN10021399 {ECO:0000313|EMBL:ELK28913.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK28913.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB108645; ELK28913.1; -; Genomic_DNA.
DR AlphaFoldDB; L5LTW2; -.
DR eggNOG; KOG4773; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd12075; SH3_Tks4_1; 1.
DR CDD; cd12078; SH3_Tks4_3; 1.
DR CDD; cd12018; SH3_Tks4_4; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR035477; SH3PXD2B_SH3_1.
DR InterPro; IPR035479; SH3PXD2B_SH3_3.
DR InterPro; IPR035480; SH3PXD2B_SH3_4.
DR PANTHER; PTHR15706:SF25; SH3 AND PX DOMAIN-CONTAINING PROTEIN 2B; 1.
DR PANTHER; PTHR15706; SH3 MULTIPLE DOMAIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF00018; SH3_1; 3.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00326; SH3; 4.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 4.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50002; SH3; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 4..128
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 151..210
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 220..279
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 367..426
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 849..910
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 126..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..585
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..621
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..735
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..779
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 910 AA; 100795 MW; F2FA79C445E55D2C CRC64;
MGRGRGVVSK EVRRSYQQKG KGDQVYIIRV TWSSGSTEAI YRRYSKFFDL QMQMLDKFPM
EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VKRLIPIDEY CKALIQLPPY ISQCDEVLQF
FETRPEDLNP PKEEHVGKKK SGSDPTSVDP MVLEQYVVVA DYQKQESSEI SLSVGQVVDI
IEKNESGWWF VSTAEEQGWV PATCLEGQDG GQDEFSLEPE EEEKYSVIYP YTARDQDEMN
LERGAVVEVI QKNLEGWWKI RHQGKEGWAP ASYLKKSSGE PLSLKLGPGS PAHTGLLDLD
GVSRPQNSGG REKEPLSSQR DGRCEGRPVP DGDVKQRSPK MRQRPPPRRD MTIPRGLNLP
KPPIPPQVEE EYYTIAEFQT TIPDGISFQA GLKVEVIEKN LSGWWYIQIE DKEGWAPATF
IDKYKKTSNA SRPNFLAPLP NEMAQLRLGE AAMENSMGGE AGGPSRPLPD APPGAVDSGI
PRSKDWKGGK DALRKASSDV PCTGYEELSD LSQEEKPSLP PRKESIIKSE GELQERERQR
LEQLRGSSPK PPGVILPMIP AKHSPPTRDG KKPEPKPDKS KVFQLKNEMG LECGHKVLAK
EVKKPNLRPI SRSKADPPEE RPEAVSQNPF LKSKPQVRPK PASSPRIEAP QGEEQVDICN
LRSKLRPAKP HEKPLLDGES SHQAVGGQDA AFSRSFLPGE GPGRAPDRTG KQDGLSPKEI
PCRPPPKPAK TMDPAPKNVP APLKEAPQEA PQQRPVIPPR RPPPPKKTSS SPRPLPEPMG
PQREANEGRA APAPGRALLV PPKAKPFLAN SSGGQDDIRG RGGLGPRLVG KMGENREKAA
AAPFPNADSP KDVYVAVANF EGDEDASSFQ EGTVFEVREK NSSGWWFCQV LSGAPSWEGW
IPSNYLRKKP
//
