ID L5LUE2_MYODS Unreviewed; 445 AA.
AC L5LUE2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Hepatocyte nuclear factor 3-gamma {ECO:0000313|EMBL:ELK29687.1};
GN ORFNames=MDA_GLEAN10003869 {ECO:0000313|EMBL:ELK29687.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK29687.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; KB107801; ELK29687.1; -; Genomic_DNA.
DR AlphaFoldDB; L5LUE2; -.
DR eggNOG; KOG3563; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd20040; FH_FOXA3; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR047366; FH_FOXA3.
DR InterPro; IPR013638; Fork-head_N.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF201; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; 1.
DR Pfam; PF00250; Forkhead; 2.
DR Pfam; PF08430; Forkhead_N; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS00657; FORK_HEAD_1; 2.
DR PROSITE; PS00658; FORK_HEAD_2; 2.
DR PROSITE; PS50039; FORK_HEAD_3; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT DOMAIN 97..173
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DOMAIN 213..307
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 97..173
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT DNA_BIND 213..307
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 31..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..54
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 445 AA; 47610 MW; 0C99FD3CCE4A738B CRC64;
MQVYSPVTPV PTMAPLNSYM TLNPLSSPYS PGGLPASPLP SGPLAPPAPT APLGPTFPGL
GASSGGGSSS GYGGPGPGLV HGKEMPKGYR RSLAHAKPPY SYISLITMAI QQAPGKMLTL
SEIYQWIMDL FPYYRENQQR WQNSIRHSLS FNDCFVKVAR SPDKPGKGSY WALLSLGASS
GGGSSSGYGG PGPGLVHGKE MPKGYRRSLA HAKPPYSYIS LITMAIQQAP GKMLTLSEIY
QWIMDLFPYY RENQQRWQNS IRHSLSFNDC FVKVARSPDK PGKGSYWALH PSSGNMFENG
CYLRRQKRFK LEEKVKKAGS GTSATRNSAG SAASTATPAA TVTSPPQPQP PPPEPEAQGG
EDVGALDCGS PSSSTPYFTG LELPGELKLD APYNFNHPFS INNLMSEQTP APPKLDVGFG
GYGAEGGEPG VYYQGLYSRS LLNAS
//
