ID L5LZ59_MYODS Unreviewed; 490 AA.
AC L5LZ59;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Forkhead box protein B1 {ECO:0000313|EMBL:ELK31342.1};
GN ORFNames=MDA_GLEAN10013437 {ECO:0000313|EMBL:ELK31342.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK31342.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; KB106269; ELK31342.1; -; Genomic_DNA.
DR eggNOG; KOG3562; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF377; FORK HEAD DOMAIN-CONTAINING PROTEIN FD4-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT DOMAIN 13..107
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 13..107
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 240..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 361..401
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 463..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 54717 MW; B34FD253284EB259 CRC64;
MPRPGRNTYS DQKPPYSYIS LTAMAIQSSP EKMLPLSEIY KFIMDRFPYY RENTQRWQNS
LRHNLSFNDC FIKIPRRPDQ PGKGSFWALH PSCGDMFENG SFLRRRKRFK VLKSDHLTLP
QMPAAAYNLG GVAQPSGFKH PFAIENIIAR EYKMPGGLAF SAMQPVPAAY PLPNQLTTMG
SSLGTGWPHV YGSAGMIDPA TPISMAXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
XXXXAARSPR AHPRLALELA PLPQPHVLAD SHQPKQPRHS QRDAHQPRLG LALGGGALTP
RRRRPLGFSI PLAPSQYLAP RPAHPDTGPP PYRVNSLSAN RLSPARTLFW TRRQNTNLRR
GLEARGSCSR PHKRGRQGHL SLAVPSPGPW KPSRVRGRGN PASRLHREER VFPPPALAGL
EPPHSLFQDQ RKRLGGVLEH ISPEGRRLPS EGRISLFKSW KSTTKRDRSS SCPARLRPSG
RGWADRSFPG
//
