ID L5M2P4_MYODS Unreviewed; 2897 AA.
AC L5M2P4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Zinc finger ZZ-type and EF-hand domain-containing protein 1 {ECO:0000313|EMBL:ELK31968.1};
GN ORFNames=MDA_GLEAN10006375 {ECO:0000313|EMBL:ELK31968.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK31968.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB105942; ELK31968.1; -; Genomic_DNA.
DR eggNOG; KOG1426; Eukaryota.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08667; APC10-ZZEF1; 1.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR InterPro; IPR040099; ZZEF1.
DR InterPro; IPR047052; ZZEF1_APC10.
DR PANTHER; PTHR22772; NOVEL ZZ TYPE ZINC FINGER DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22772:SF4; ZINC FINGER ZZ-TYPE AND EF-HAND DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM01337; APC10; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 31..59
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 161..340
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT DOMAIN 1751..1806
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 150..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1378..1470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1918..1999
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2346..2379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1378..1402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1440..1456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1942..1956
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1957..1996
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2359..2379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2897 AA; 323907 MW; 9147B7B1BFF73C48 CRC64;
MKGPCPNWFG SVDRVSACGL KGPRYDSSQG QAFAQFDAEG DGTVDAESML EALKNSSGAN
LQGELSHIIR QLQACSLVPG FIDIFSESKE GLGVHSSMIL RFLHRNRLSS IVIPYPMLDH
CNNMCTMRAS VLKESLDELV QKEKAETAVV EEQDPHTAHE APSVDIESPG DLTGSPEMDK
LKSIAKCYAY IETSSNPTDI DKMTNGETSS YWQSDGSARS HWIRLKMKPD VVLRHLSIAV
AATDQSYMPQ QVTVAVGRNA SDLQEVRDVH IPSNVTGYVT LLENANISQL YVQINIKRCL
SDGCDTRIHG LRAVGFQRVK KSGVSVSDAS AIWYWSLLTS LVTASMETNP AFVQTVLRNT
QKALQHMPPL SLSPGSTDGS TFLSPNVLEE VDSFLIRITS CCSTPEVELT LLAFALARGS
VAKVLSSLCT VTDHLDTHYD ASSLISSMAS VRQNLLLKYG KPLQLTLQAC DVKGKEEKSG
PENLLVEPWT RDGFLTETGK TRASTIFSTA TESALQVTQI RIMVRRGGIG AQCGLIFAYN
SSSDKFHAEE HFKRFEKYDK WKLKEFRQFV KSRIGCSPDD LGEDDPIGWF ELEEEWDEAE
IKLQQCRIAR YLMVKFLCTR QESAERLGVQ GLSISGYLRP ARAEAEQSAI CAHCRKDMEE
SVCGASLLLR TLQFIQQLAH DLVQQKESGL KYKSFLDFAG LDLEIFWNFY RKLKQNPREE
CISAQTLLLQ LLQSCFLVLQ KDSTAASEDA KAPRQSPRAV EAAKELYTHL CDVVDRVDGD
SVPMEILKQE VRNTLLSGAA IFFPDRQTQR NHLFSMMKNV TEQEHKQSLQ LTFRSLCTYF
SDRDPGGLLL LPEKGDLADT NISEVLAVMR TLLSVAAREC ELLMLNKAQA EVGSVLFSLF
WSVQGSLLSW CYLQLKSTDP GAKELAIDLI EKYVEQFLGS TRVILESLLS QYSGKTIVEK
LCNSVFSMAA RQLVIFLLDF CTLDISHCKL LREFSTLTEL LKRLCSDPEG GLNKLDVETW
QQEQPVVLHT WTKESAHNYE NNCHEVSVFV SPGATYFEVE FDERCETEKS QADGCQYSGG
GGSLSCLLSS AKDVRKKKVT FKAGPRLQFL FHSDSSNNEW GYKFTVTAYG LPDVAVSWGL
DLQLLVCRLM GRLASQCMAL KSVHQLGSNM AVPQAKMALV LNSPLWKPVF RHQICPELGL
EASWPTHPQQ DSKEVKNIPD DPCHRFLLDF AQSDPAQNFC GPYSELFKGF IQACRKQAPK
TDIVAGSTID QAVNATFAAL VYRTPDLYEK LQKYVNSGGT TALSEEFAQV YSLADGIRIW
MLEIKQKSLV SLGNEAEEKR GSEAAEANPE SLAKECIQKS LLLLKFLSMG ISSKESSDKL
VTTDEPDHHL QPLDKRQRTS SVVEEHFQAS ASPTDAAPPA AGDRSPGLDV QPKLPPSSGP
PATEVSSATA EEPSSPSTPT RRPPFTRGRL RLLSFRSMEE TRPVPTVKEK YPVLRDVMDF
IKDQSLSHES VVKVLSLRKA QAQSILEVLK IIQYCAEALG QPHCFHPPYI LFLLELLTCQ
KEFTNYFGHL EGCGAALHKE IRDTYYRFVL FMVKAIKGFS SINDRSLLPA LSCVQTALLH
LLDMGWEPSD LTFFVDIQLP DLLMKMSQEN ISVHDSVISQ WSEEDELADA KQNSEWMDEC
QDGMFETWYE KIAQEDPEKQ RKLELGDVKE TLESECIAIQ SRKSSARGVS ICPCLGGVKP
EGHGDDHEMV NMEFTCDHCQ GLIIGRRMNC NVCDDFDLCY GCYAAKKYSY GHLPTHSITA
HPMVTIRSSD RQRLIQPYIH NYAWLLFAAL ALYSAHLASS EEVDGEKLDP QARSCAVTLR
SQCMQLVGDC LMKAHQGKGL KALALLGVLP DGNSTPGNQA PPVIVPTRTA EEQLEKEAVQ
VAEEPADTGP FVHCNGENGV HKEGIPLDHK QRNKADESGS CQTQISDSPA DATTPTGLSD
ADNLGASSQK PVEEKTVTPS PEQVFAECSQ KRILGLLAAM LPPLKLQDPT VPLIDLEHVL
PLMFQVVISN AGHLNETYHL TLGLLGQLII RLLPSEVDAA VIKVLSAKHN LFAAGDNSIM
PDGWKTTHLL FSLGAVCLDS RVGLDWACSM AEILRSLNSA PLWRDVIATF TDHCIKQLPF
QLKHTNIFSL LVLVGFPQVL CVGTRCVYMD NANEPHNVII LKHFTEKNKA VIVDVKTRKR
KTVKDYQLVQ KGGQECSDSQ AQLSQYSQHF AFIASHLLQT SMDSHCPEAV EATWVLSLAL
KGLYKTLKAH DFEETHATFL QTDLLKLLVK KCSKGTGFSK TWLLRDLEIL SIMLYSSKKE
INTLAEHGDL ESDERGDQEE EVERSVSSPS EPEQKKLDPL ESLDEPTRIC FLMAHDALNA
PLHILRAIYE LQMKRTDSFF LEVQKRFDGD ELTTDERIRA LAQKWQPSRS LRLEEQSAKA
VDTDMIILPC LSRPTRCDQA TAESNPVTQK LISSTESELQ QSYAKQRRTK SAALLHKELN
CKSKRAVRDY LFRVNEATAI LYARHVLASL LAEWPGHVPV SEDILELSGP AHMTYIFDMF
MQLEEKHRWE KILQKVLQGC RENMLGTMAL AACQFMEEPG MEVQVRESKH PYNNNTNFED
KVHIPGAIYL SIKFDSQCNT EEGCDELAMS SSSDFQQDRH NFSGSQQKWK DFELPGDTLY
YRFTSDMSNT EWGYKFTVTA GHLGRFQTGF EILKQMLSEE RVVPHLPLAK IWEWLVGVAC
RQTGHQRLKA IHLLLRIVLC CNHSDLCDLS LLKPLWQLFT HMEYSLFEDV TQPGILLPLH
RALTELFFVT ENRAQELGLL QDYLLALTTD DHLLRCAAQA LQNIAAISLA INYPNKATCL
XXXXXXXXXX XXRNQRI
//
