ID   L5MCS5_MYODS            Unreviewed;      2205 AA.
AC   L5MCS5;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Hydrocephalus-inducing protein like protein {ECO:0000313|EMBL:ELK36191.1};
GN   ORFNames=MDA_GLEAN10016775 {ECO:0000313|EMBL:ELK36191.1};
OS   Myotis davidii (David's myotis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK36191.1, ECO:0000313|Proteomes:UP000010556};
RN   [1] {ECO:0000313|Proteomes:UP000010556}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB101785; ELK36191.1; -; Genomic_DNA.
DR   Proteomes; UP000010556; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR031549; ASH.
DR   InterPro; IPR033305; Hydin-like.
DR   InterPro; IPR033768; Hydin_ADK.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23053; DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1; 1.
DR   PANTHER; PTHR23053:SF0; HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG; 1.
DR   Pfam; PF15780; ASH; 1.
DR   Pfam; PF17213; Hydin_ADK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010556}.
FT   DOMAIN          513..606
FT                   /note="Abnormal spindle-like microcephaly-associated
FT                   protein ASH"
FT                   /evidence="ECO:0000259|Pfam:PF15780"
FT   DOMAIN          1934..2131
FT                   /note="Hydin adenylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF17213"
FT   REGION          950..973
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1857..1878
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2051..2090
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1409..1440
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        952..966
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2205 AA;  248306 MW;  C0A8AB1B0F35BF5A CRC64;
     MLKGFQSKVL PPLSPKVVKE EDVNQMLTPS EFLKEMSLTT EQRLANTRLM CRPQIIELLD
     MGEATHQKFS DIDLDQALFQ PFPSEIIFQN YTPCEVYEVP LVLRNNDKIP RMVKVIEESS
     PYFKVISPKD IGHKVAPGVP SIFRILFTPE ENKDYAHMLT CVTEREKFIV PIKARGARAI
     LDFPDKLNFS TCPVKYRTQK ILLVRNIGNR DAVFHITTYW HSPKISLHCR LLFLIHDSHI
     QSAPFSVEPS VGTLTVGESM QLEVDFEPQA VGNHSKRLIV YYDTDRSILI GLWACHQDSH
     KFNLERYLIN RERTSSPQFK TVITECSVTR VAWSIGRWMA VTFPCQVVCE DLNKEEKDET
     DEFLEEFVSD PLLRERISIL SRTFANQRRL VQADSILFLN NIFIIEPLEG DVWPNSSAEI
     TVYFNPLEAR LYQMTVYCDI SGREIRLPLR IKGQGMGPKI HFNFELLDIG KVFVGSVHCY
     EAILSNKGSI DALFNVISPT SALGACFVFS PKEGIIKPSG VQAVQISFCS SILGHFEEKF
     LVSVSGSPEP VKLTIRGCVI GPTFHFNVPA LHFGDVSFGF PHTLICSLNN TSLVPMTFKL
     RIPGDGHESI SSCEQYTDTK GPSWNKEEIP ITKPKEFTIT PNCGTIRSQG FAAIRVTLCS
     NTVQKYELAL VVDVEGIGEE VLALLITARC IVPALHMATA EVDFGRCFLK YPYEKTIELV
     NPDDLPGCYE VLPQIDEDSP AVLLSSPNPY GIIPPQSTVH IPLILETQVT GEHRTTIYIS
     VFGSQDHPVV CQLRSIGEGP VICVSPHQVD FGKIYVLTES SRVINLSNQS LIPGLFRAHM
     AHKKSLWTVE PSEGTVPPED DIQLTVTANL NDILMFKDTV LLDIINSNTY RISVQAEGIG
     STIVSDKPFA PELNLGAHFS LDTCYYHFKL TNKGRRVQQL FWMNEKFQPK NKKGAPKRRL
     AKRPRAQAAR RPQSPVFQLQ PFRMELYPDQ TVDVILDGYS ATPRMVKEKL VCHAIIGAQR
     ERSLVMTVDV MCEFIAPLIQ LSTKKLVYRL EKKPQTVLQP DYQPLVMKNI SMLPVNVLLS
     TSKPFFICDT EQSLLPLIPE PIKLEIGEEK SLLVKFDPTH KCDLNNWVAE ETLAIRYLEH
     PQVDSLSLRG EVHYPNLSFE TMDLDFGCIL NDTEVIRYVP ITNCSPLAVK FCWFFLESDE
     ENQIRTTLVD EDTASEEGEP RRAEAPKLIN SDVFDILPLY GELQPYSSDQ IAFTFYGHCD
     IIAQATALCK VEGGPNYEVK LRGETSMVSY SFDTKDINYG LQLFDRITET KVTLKNTGKV
     GFEFRVLTND QSSSDSLLPG VPLILPLSGF ISSLKEQELK IYYLPGVPEI FQRSFQVQIA
     HLDPETITLS GEGIFPRIYI DLPRNLKGNE KYEIFLNQAR ENLENELDKD ETLNHAETIE
     EMSEDEPFKL SAQLQMEVER LIVQNYSMEH QKIIHDPLDE VSHRGRHRLA KIQLPEYILD
     FGHIILGDSR SHIIKITNTS HIPVSFHAEK RILHDTGFST ELDRVKHLPY CETETFEVRF
     DQQGTNQSVG NKEAILPIKV VGGPTVHICL QVQVTIPTMT LSCDKVEFAT IQCGQCLVET
     IQLSNHLQVP CEWFVVSHKP FNKLEKHMPK YLRRKLHTEF KPKTRIFEIQ PTTGVLDPGE
     KANVQVRFMP KEEKFYSQTL TFQLVRSTQK LTLLAQGQGL EPRLEFSPSI LELGPLLPYA
     PGDEAEVVVK NPCDFPIEFY SLEFDQQYLI EEKILRSLKG YDSYNTLLLP PRVPGEKLPS
     EVYEYFREMK QSKEEQMKAK YLEALAQDNE DEDIPLSEQV TVSNVKRGSL SRGISVTSDL
     EDWEESKNNP DDEEDDDSLE KLVFQTEKLQ STDSHSAEDD GDVENNPVNR AIARYLGIDV
     SAEGNLAKNR KGIAIIVHGT PVSGKTATAA SLAKYYGAAC FNIDSIVLEA ICDGNSIPGI
     RARELCIRAA IEQSIREGEE SAQETTSSQP GVGQIRQSSE NLGKLISETT LINPEVKSAK
     SVRGSMLFSK TRAEHGSGSQ RQHHPHPPET PQISSSPLPS GPTPRRLSVS TSIGGETGLL
     SCVLPEEMLV QILAERLQLS DCNLGVVFDS LDTLFARNAA IALLCLLKAI GNREHIYVLN
     MPQDYAGMKA QEKAKKEQEG KAHALLDCPS QALTSLSFTY RICPF
//