ID L5MDW3_MYODS Unreviewed; 438 AA.
AC L5MDW3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=General transcription factor IIE subunit 1 {ECO:0000313|EMBL:ELK36450.1};
GN ORFNames=MDA_GLEAN10018592 {ECO:0000313|EMBL:ELK36450.1};
OS Myotis davidii (David's myotis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=225400 {ECO:0000313|EMBL:ELK36450.1, ECO:0000313|Proteomes:UP000010556};
RN [1] {ECO:0000313|Proteomes:UP000010556}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the TFIIE alpha subunit family.
CC {ECO:0000256|ARBA:ARBA00008947}.
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DR EMBL; KB101593; ELK36450.1; -; Genomic_DNA.
DR RefSeq; XP_006755413.1; XM_006755350.2.
DR AlphaFoldDB; L5MDW3; -.
DR GeneID; 102774156; -.
DR KEGG; myd:102774156; -.
DR CTD; 2960; -.
DR eggNOG; KOG2593; Eukaryota.
DR OrthoDB; 5395944at2759; -.
DR Proteomes; UP000010556; Unassembled WGS sequence.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR Gene3D; 6.10.140.1250; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039997; TFE.
DR InterPro; IPR017919; TFIIE/TFIIEa_HTH.
DR InterPro; IPR002853; TFIIE_asu.
DR InterPro; IPR021600; TFIIE_asu_C.
DR InterPro; IPR024550; TFIIEa/SarR/Rpc3_HTH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13097:SF8; GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1; 1.
DR PANTHER; PTHR13097; TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT; 1.
DR Pfam; PF11521; TFIIE-A_C; 1.
DR Pfam; PF02002; TFIIE_alpha; 1.
DR SMART; SM00531; TFIIE; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51344; HTH_TFE_IIE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010556};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..104
FT /note="HTH TFE/IIEalpha-type"
FT /evidence="ECO:0000259|PROSITE:PS51344"
FT REGION 332..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 438 AA; 49389 MW; 59F5A1BDB3870153 CRC64;
MADPDVLTEV PASLKRLAKY VIRGFYGIEH ALALDILIRN PCVKEEDMLE LLKFDRKQLR
SVLNNLKGDK FIKCRMRVET AADGKTTRHN YYFINYRTLV NVVKYKLDHM RRRIETDERD
STNRASFKCP VCFNTFTDLE ANQLFDPRTG TFRCTFCNTE VEEDESAMPK KDARTLLARF
NEQIEPIYAL LRETEDVNLA YEILEPEPTE IPALKQSKDR AATTAGAAGL SSGHHREAWA
TKGPSYEDLY TQNVVINMDD QEDLHRASLE GKSAKERPVW LRESTVQGAF GPEEMKEGGL
DIDAFQDREE GRAGLDDNEE VMRALLIHEK KTPSATAGSV GAAAPVTAAN GSDSESETSE
SDDDSPPRPA AVAAHHREDD EEDDEFEEVA DDPIAMVAGR PFSYSEVSQR PELVAQMTPE
EKEAYIAMGQ RMFEDLFE
//
