ID L5N0Q7_9BACI Unreviewed; 1415 AA.
AC L5N0Q7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Peptidase S8 and S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:ELK44399.1};
GN ORFNames=D479_19334 {ECO:0000313|EMBL:ELK44399.1};
OS Halobacillus sp. BAB-2008.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=1246484 {ECO:0000313|EMBL:ELK44399.1, ECO:0000313|Proteomes:UP000010769};
RN [1] {ECO:0000313|EMBL:ELK44399.1, ECO:0000313|Proteomes:UP000010769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAB-2008 {ECO:0000313|EMBL:ELK44399.1,
RC ECO:0000313|Proteomes:UP000010769};
RX PubMed=23469348;
RA Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Saxena A.K.,
RA Bagatharia S.B.;
RT "Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain
RT BAB-2008.";
RL Genome Announc. 1:E00222-12(2013).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELK44399.1}.
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DR EMBL; ANPF01000099; ELK44399.1; -; Genomic_DNA.
DR PATRIC; fig|1246484.3.peg.3926; -.
DR eggNOG; COG1404; Bacteria.
DR eggNOG; COG2247; Bacteria.
DR OrthoDB; 9798386at2; -.
DR Proteomes; UP000010769; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 3.40.50.12090; -; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR007253; Cell_wall-bd_2.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF04122; CW_binding_2; 3.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000010769};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..1415
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039286322"
FT DOMAIN 172..635
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT REGION 137..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 181
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 382
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 591
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1415 AA; 150923 MW; 1BA7E0C26908134A CRC64;
MVSNKKNMKK KALSVLASAA IVASSFAGVS TYSPGAVQAE TKAPKTFNTL LNQEEVLKLA
NNEAATQELV IIGNGKTDAT QQLEKLGVKV KQNHKNYGYL ADVPTNKILD VVKLDSVRTV
GENAKVELAP LEPKELNADK QSAVDPKADV TPDQLETHPA TGVDEIQDKF SGEGIRVGII
DSGPDPGHES FTEQPDDADF AETRKFGDSK ITEVRDYTIS DFHAANTGVY PLEDKYAEYL
ENEPYGYFSE GDVVFMEIPE ELEDAFSLDE INPDGEDAYF GSTHFNALAD LNGDGSEEVD
EDGNPVMDNF GVLLVGDEVY IDTDIDGDFT DETAYKDGEA GTFDVDVTDE TVGANFRVND
MNRYEEDFGI KTVNLFTDLN GHGSHVAGIS AADGPLRSNA YGAVAGEGVA PGADIVGMRV
FQEDGGAYTW SIQTAMIDAA LPESEGGFGV DVANLSLGSS PDLNDGTGSY GELMTLLSDD
FDIVFVTSAG NAGPGIDTVG SPGDVGSVIS VGAYINSEMW AKEYNNFPYG KDKDGNPLDG
EGLWYFSSVG PNEAGDQKPD IVAPGSAYAA QPVHQYQAEG QTAYDVLQGT SMSAPYVAGA
VAVLKSAAEK DRMPFDYELA REALIQTARE LDGYDRAQQG GGLIDVPAAY EYMRDNFISE
VKDVDVTVFH GEKVAGGPGL YVRNKDIPET VEVLVHNTSD EAKKLEVKAS DDWFTPSVKE
VSLGAGEYKY ITVNYDAEKL KTGVNAGTLT FDDPSTPYVE ARSAQTIVTG YEFTKENKHR
FRATDEVQAA QTKGYTFDVD SGVSELRFTL DAVTEGGEEQ ARVRLMVFDP DGVQVNVPST
GYAGYDGKDL DEYVASSPKQ GVWEVHVYGA TNPEQGKEMN KYTLDAVAQD FVSEPGRIDL
GKVSSSEKID KEVTFTNYMK DAKDVKFETV GFTGPIKDTI KGTVKQDTEA SQVDGEVIDI
DIENNVSLSV DVAPAAPADL DLFLFRDGEL VAASASASDS EAFSVKGLPD GQYQIAVDYF
GTGTASVDYT LNMTEEKVLS YDSEDKGEGS VKAGKDAAKV DVGQSVTVPV SITTPEKSIK
GYSALYMVDK ATDEVLDLVP ITTDADIVQV LSGKERVGTA IEISKELYPN GGADTVIVTT
GFNFPDALSA GPLASAAEAP IIPVNSKGKL TDAALKEIKR LGAKNVYLLG GEGAVSKEVF
SQLNTISIAS DKVERLSGDT RYETNLAIAD ELQNSFGFEG NGVFLATGKN YADALSAASL
AGAEGMPIVL TDGKKLSKEA MAILEDEDVY VVGGTGVISD DLVNQVDKKA LSVERLSGTN
RYGTLVSLLK EFGPNTGELY VASGRNYPDA LAAAPLVTGN GGSLLLVDPE KLPKELDAYL
TKYVYTTDVT SVTVLGGDGA VSPAVKEALQ KKVTE
//
