ID L5NEF5_9BACI Unreviewed; 434 AA.
AC L5NEF5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Na+/H+ antiporter family protein {ECO:0000313|EMBL:ELK48897.1};
GN ORFNames=D479_01350 {ECO:0000313|EMBL:ELK48897.1};
OS Halobacillus sp. BAB-2008.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=1246484 {ECO:0000313|EMBL:ELK48897.1, ECO:0000313|Proteomes:UP000010769};
RN [1] {ECO:0000313|EMBL:ELK48897.1, ECO:0000313|Proteomes:UP000010769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAB-2008 {ECO:0000313|EMBL:ELK48897.1,
RC ECO:0000313|Proteomes:UP000010769};
RX PubMed=23469348;
RA Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Saxena A.K.,
RA Bagatharia S.B.;
RT "Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain
RT BAB-2008.";
RL Genome Announc. 1:E00222-12(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELK48897.1}.
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DR EMBL; ANPF01000002; ELK48897.1; -; Genomic_DNA.
DR RefSeq; WP_008632781.1; NZ_ANPF01000002.1.
DR AlphaFoldDB; L5NEF5; -.
DR PATRIC; fig|1246484.3.peg.282; -.
DR eggNOG; COG2056; Bacteria.
DR OrthoDB; 9772446at2; -.
DR Proteomes; UP000010769; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000010769};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..88
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 143..428
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 434 AA; 45926 MW; 54E5AA82F3415A80 CRC64;
MAWAVVVSVL VMTVLSLLRV NVIVAILAAG LTAGLMNGET LTSSLEILVN GMGEQASVAL
SYILLGAFAI AISYSGITTI LVSYLLRVLK NKRTMIVFVI AFVASLSQNV IPVHIAFIPI
LIPPLLKLFD EMKLDRRAVA AALTFGLKAP YVMIPVGFGY IFHQTIQKSM ESNGIELSIG
TIAQSLIIPG SGMIVGLLIA VLITYRKPTV VNEQQANEED VLVQTQDQKF NKKHVLTIVA
IIVTLVIQAV WANLVLAALA GIVLMFAFRV VPYSKGDKVI NDGIAMMGFI AFVMLVASGY
ANVLTTTESV SALVEVSSDY LGNNQAFIAF ILLLVGLVVT MGIGSSFATI PILAALFVPI
CVAAGFSPLA TAALIGTAGA LGDAGSPASD STLGPTSGLN ADGRHNHIWD TCVPTFLHYN
IPLFIFGWAA SLFL
//
