ID L5NF32_9BACI Unreviewed; 716 AA.
AC L5NF32;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Minor extracellular serine protease {ECO:0000313|EMBL:ELK49045.1};
GN ORFNames=D479_00405 {ECO:0000313|EMBL:ELK49045.1};
OS Halobacillus sp. BAB-2008.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=1246484 {ECO:0000313|EMBL:ELK49045.1, ECO:0000313|Proteomes:UP000010769};
RN [1] {ECO:0000313|EMBL:ELK49045.1, ECO:0000313|Proteomes:UP000010769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BAB-2008 {ECO:0000313|EMBL:ELK49045.1,
RC ECO:0000313|Proteomes:UP000010769};
RX PubMed=23469348;
RA Joshi M.N., Pandit A.S., Sharma A., Pandya R.V., Saxena A.K.,
RA Bagatharia S.B.;
RT "Draft Genome Sequence of the Halophilic Bacterium Halobacillus sp. Strain
RT BAB-2008.";
RL Genome Announc. 1:E00222-12(2013).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELK49045.1}.
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DR EMBL; ANPF01000001; ELK49045.1; -; Genomic_DNA.
DR RefSeq; WP_008632346.1; NZ_ANPF01000001.1.
DR AlphaFoldDB; L5NF32; -.
DR PATRIC; fig|1246484.3.peg.84; -.
DR eggNOG; COG1404; Bacteria.
DR Proteomes; UP000010769; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02133; PA_C5a_like; 1.
DR CDD; cd07474; Peptidases_S8_subtilisin_Vpr-like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034213; S8_Vpr-like.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000010769};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 118..503
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 313..389
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT ACT_SITE 127
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 165
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 454
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 716 AA; 77215 MW; 41519CAB34231E92 CRC64;
MRLWLLAVMA FALLTGFDPP DPPEPSEEVT IIVEVEEKPS DFQEMLEARL PRLEVVAVYD
RLFNGLAVRG KAEELEKLAR MDMVTNQYPV QTYRALGDDE MTFSTEKLRE NLSSSYTGKG
VKVGVIDTGV DYTHPDLRKN YNGGFDTVDF DNDPMETKGE GATAHGSHVA GVIAADGKMK
GIAPDARIYA YRALGPGGVG SSVQVIAALE KAVKEGMDVI NLSLGNDVNG PDWPTTHAVN
KAVELGTVVV VAAGNSGPDA WTVGSPATSS EAITVGASAL SMKIPVLKVP GVRAKVPLQL
FAGSKQWQLS RKYPVVYAGK GEGHLGDLRG KIALVERGTI PFVEKAIKAY QAGAVAVLIY
NNEEGAFQGS LDGQKLPVPV ASLSKEAGEF LVEEAVAQNQ WVATEWDTLN DRIAPFSSRG
LVTTNWEIKP DIVAPGVNIW STVPGGYQPM QGTSMAAPHV AGAAALLKEA HPEWTPAQVK
TALASTAIPI NGEDSLPMEQ GAGAMDIGKA LHPDLMIDHG ALAFGKVEGA FYKKKIRFRV
TNPTDEVVRL EMDQPNMKHG ESWSVPLSFD LLPAEEKEVE VELRLTTSLL DPGVHQGYLT
MRGNGKEYLL PYAYVNEKAS YQQISGFELV DEGKGKEASY RFHLAEEVER ITVDLYRAGS
FFYAGELLDI DNPDAGMKEG TAKLAADSLA GSYIAVALVE TKDGIEHYAF PVYMEG
//
