ID L7F5I6_9ACTN Unreviewed; 454 AA.
AC L7F5I6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Terpene synthase {ECO:0000256|RuleBase:RU366034};
DE EC=4.2.3.- {ECO:0000256|RuleBase:RU366034};
GN ORFNames=STRTUCAR8_01058 {ECO:0000313|EMBL:ELP66542.1};
OS Streptomyces turgidiscabies Car8.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698760 {ECO:0000313|EMBL:ELP66542.1, ECO:0000313|Proteomes:UP000010931};
RN [1] {ECO:0000313|EMBL:ELP66542.1, ECO:0000313|Proteomes:UP000010931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Car8 {ECO:0000313|EMBL:ELP66542.1,
RC ECO:0000313|Proteomes:UP000010931};
RX PubMed=21087627; DOI=10.1016/j.plasmid.2010.11.002;
RA Huguet-Tapia J.C., Badger J.H., Loria R., Pettis G.S.;
RT "Streptomyces turgidiscabies Car8 contains a modular pathogenicity island
RT that shares virulence genes with other actinobacterial plant pathogens.";
RL Plasmid 65:118-124(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(E)-2-methylgeranyl diphosphate + H2O = 2-methylisoborneol +
CC diphosphate; Xref=Rhea:RHEA:32571, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:61984, ChEBI:CHEBI:61987;
CC EC=4.2.3.118; Evidence={ECO:0000256|ARBA:ARBA00035573};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|RuleBase:RU366034};
CC -!- SIMILARITY: Belongs to the terpene synthase family. 2-methylisoborneol
CC synthase subfamily. {ECO:0000256|ARBA:ARBA00035653}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELP66542.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEJB01000343; ELP66542.1; -; Genomic_DNA.
DR RefSeq; WP_006378372.1; NZ_AEJB01000343.1.
DR AlphaFoldDB; L7F5I6; -.
DR STRING; 85558.T45_03150; -.
DR PATRIC; fig|698760.3.peg.4711; -.
DR Proteomes; UP000010931; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010333; F:terpene synthase activity; IEA:InterPro.
DR GO; GO:0042214; P:terpene metabolic process; IEA:InterPro.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR047945; MIB_synthase.
DR InterPro; IPR034686; Terpene_cyclase-like_2.
DR NCBIfam; NF041167; f2_encap_cargo2; 1.
DR PANTHER; PTHR35201; TERPENE SYNTHASE; 1.
DR PANTHER; PTHR35201:SF4; TERPENE SYNTHASE; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01020; Terpene_Cyclase_Like_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU366034};
KW Magnesium {ECO:0000256|RuleBase:RU366034};
KW Metal-binding {ECO:0000256|RuleBase:RU366034};
KW Reference proteome {ECO:0000313|Proteomes:UP000010931}.
FT REGION 37..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49239 MW; 4E4EABFEE740D815 CRC64;
MPAPEPTSPQ SSLPSAAARV GAQVLAEAAA RACDIRTVTG GSPGELSSPA PSALSVPAPP
PPVAPTAAVP TVAVPSAVVP PAPTAVGPTP ILGLERILRG PSGLGTADLR LVLREQLSTP
AEPLAASAEG NPIPGLYHHQ VAEPDPVRVE EVSRRIKSWA LDEVSLYPED LAEQFDGFSV
GRYMVGCHPD APTVDHLMIA TRLMVAENAV DDYYCEDHGG SPVGLGERLL LAHTALDPLY
TTEEYQGQWA KSLHADAPRR AYRSAMNYFV QVASPSQSDR FRHDMARLHL GYLAEAAWAQ
LDHVPEVWEY LAMRQFNNFR PCPTITDTIG GYELPTDLHA QAAMQKVIAL AGNATTIVND
LYSYTKELDA PGRHLNLPVV IAEREGLSDR DAYLKSIEVH NDLMHDFETN SAALAADCPV
PTVQRFLRGV AAWVDGNHHW HRTNTYRYSL PDFW
//
