ID L7FL91_ENTIV Unreviewed; 567 AA.
AC L7FL91;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=EIN_242160 {ECO:0000313|EMBL:ELP86902.1};
OS Entamoeba invadens IP1.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=370355 {ECO:0000313|EMBL:ELP86902.1, ECO:0000313|Proteomes:UP000014680};
RN [1] {ECO:0000313|EMBL:ELP86902.1, ECO:0000313|Proteomes:UP000014680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IP1 {ECO:0000313|EMBL:ELP86902.1,
RC ECO:0000313|Proteomes:UP000014680};
RA Zafar N., Inman J., Hall N., Lorenzi H., Caler E.;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KB206893; ELP86902.1; -; Genomic_DNA.
DR RefSeq; XP_004253673.1; XM_004253625.1.
DR AlphaFoldDB; L7FL91; -.
DR EnsemblProtists; ELP86902; ELP86902; EIN_242160.
DR GeneID; 14885880; -.
DR KEGG; eiv:EIN_242160; -.
DR VEuPathDB; AmoebaDB:EIN_242160; -.
DR OrthoDB; 2962512at2759; -.
DR Proteomes; UP000014680; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR004868; DNA-dir_DNA_pol_B_mt/vir.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR33568; DNA POLYMERASE; 1.
DR PANTHER; PTHR33568:SF3; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF03175; DNA_pol_B_2; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014680}.
FT DOMAIN 350..567
FT /note="DNA-directed DNA polymerase family B
FT mitochondria/virus"
FT /evidence="ECO:0000259|Pfam:PF03175"
SQ SEQUENCE 567 AA; 67003 MW; 363119A6B543B85E CRC64;
MCFINKQEVN DSIDSTFYVQ QTIPEPLFIL ELKISPYLYT EDLIHQYKTT GGSFFPYHYK
PEFEIFGQYL AKAQIFSSLI NENEKVRSEF DLNCFTYALK QANVDDETLE LVLIHCRGRY
QKAKMLDELC KSAHIRIRID RENTDKSNKH KNRKIDYYGC ELKDAKYNLE MFLYRDSLMK
GDHYILNIDI PITPFYLKNR EELDNWAITH NLSIKSMFNK QRYNKNKQCY EVKDKNSNTI
KLSDLIIYIR DHNGFEPYSL SDVLHLKSDL SEYVLQSLNT LEYLPFETRK IEIKENKRKE
VDHSYWYADF EASTQGYHNP YCVCYSKRGE DKIYNKYGKD CAYDFLCDLP HNAVCYFHNL
KYDGSFLAKY GVNRCIKKSG KIMQITLKFQ GKQLTFKDSY ALISTSLASF PKMFGLSNIQ
KEIYPYNYYG PGGLRRETSY NQERVESNIG NILEADLYEI QQWNEDQFKL FVKNIDSIDN
CRTDEYHFNM KAYCVFYCNQ DVRILKQGHS KFRDMCLEYL NIDVDKVISA ASLANTYFKH
NVYSKINNLK EYGGKVREFI QGAIYGG
//
