ID L7JYU5_TRAHO Unreviewed; 324 AA.
AC L7JYU5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=26S proteasome regulatory complex, ATPase RPT4 {ECO:0000313|EMBL:ELQ76191.1};
DE EC=3.4.25.1 {ECO:0000313|EMBL:ELQ76191.1};
DE EC=3.6.1.3 {ECO:0000313|EMBL:ELQ76191.1};
GN ORFNames=THOM_0840 {ECO:0000313|EMBL:ELQ76191.1};
OS Trachipleistophora hominis (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC Trachipleistophora.
OX NCBI_TaxID=72359 {ECO:0000313|EMBL:ELQ76191.1, ECO:0000313|Proteomes:UP000011185};
RN [1] {ECO:0000313|EMBL:ELQ76191.1, ECO:0000313|Proteomes:UP000011185}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23133373; DOI=10.1371/journal.ppat.1002979;
RA Heinz E., Williams T.A., Nakjang S., Noel C.J., Swan D.C., Goldberg A.V.,
RA Harris S.R., Weinmaier T., Markert S., Becher D., Bernhardt J., Dagan T.,
RA Hacker C., Lucocq J.M., Schweder T., Rattei T., Hall N., Hirt R.P.,
RA Embley T.M.;
RT "The genome of the obligate intracellular parasite Trachipleistophora
RT hominis: new insights into microsporidian genome dynamics and reductive
RT evolution.";
RL PLoS Pathog. 8:E1002979-E1002979(2012).
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; JH993862; ELQ76191.1; -; Genomic_DNA.
DR AlphaFoldDB; L7JYU5; -.
DR STRING; 72359.L7JYU5; -.
DR VEuPathDB; MicrosporidiaDB:THOM_0840; -.
DR HOGENOM; CLU_000688_2_2_1; -.
DR InParanoid; L7JYU5; -.
DR OMA; DHEPCVI; -.
DR Proteomes; UP000011185; Unassembled WGS sequence.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF155; 26S PROTEASOME REGULATORY SUBUNIT 10B; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Hydrolase {ECO:0000313|EMBL:ELQ76191.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:ELQ76191.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011185}.
FT DOMAIN 101..240
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 324 AA; 36250 MW; 35602A84B5373CA9 CRC64;
MKKFIVKTSQ GPRYVVGARK SIDRNLLIGG TRVALDITTL TIMKVLPREI DPSIFAMTEE
NPGNVDFGKI GGLTEQITQL KEIITLPLDT PEIFERVGIS EPKGVLLYGP PGTGKTLLAR
AIAATMDVSF LKVVASSLIE KYIGESSRMI REMFQYARER TPCIIFIDEI DAIGGKRSTE
SSSSDREVQR TLMELLNQLD GFKSLDKVKV IMATNRPDIL DPALLRPGRL DRKIEIPLPN
DTGRKEILKI YIREMTCSER IDLDMLVKLS VGFNGADLRH CCTEAGMNAI RDERDAVCQE
DFVKAIRKIA GTKKLETKMD YKKP
//
