ID L7KLR5_9ACTN Unreviewed; 680 AA.
AC L7KLR5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Putative acetoacetyl-CoA synthetase {ECO:0000313|EMBL:GAC48897.1};
GN ORFNames=GOACH_07_01830 {ECO:0000313|EMBL:GAC48897.1};
OS Gordonia aichiensis NBRC 108223.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1220583 {ECO:0000313|EMBL:GAC48897.1, ECO:0000313|Proteomes:UP000010988};
RN [1] {ECO:0000313|EMBL:GAC48897.1, ECO:0000313|Proteomes:UP000010988}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108223 {ECO:0000313|EMBL:GAC48897.1,
RC ECO:0000313|Proteomes:UP000010988};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia aichiensis NBRC 108223.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC48897.1}.
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DR EMBL; BANR01000007; GAC48897.1; -; Genomic_DNA.
DR RefSeq; WP_005174549.1; NZ_BANR01000007.1.
DR AlphaFoldDB; L7KLR5; -.
DR STRING; 1220583.GOACH_07_01830; -.
DR eggNOG; COG0365; Bacteria.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000010988; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010988}.
FT DOMAIN 37..95
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 107..446
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 564..639
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 680 AA; 72648 MW; 56BAE233F1535F37 CRC64;
MSGSTASGSL DQRQKNGRID EFAATVAERH GVDTSTYEAL WSWSVAQPAK FWRAVWDFFD
LDAIAGPLAE GDDAVLASTD MPGAQWFPGV SINYVDQVFR HADAPDAANR TAVVGVDEAG
ERKSLTWSQL REQSVAFAQT LRGLGVGVGD VVAAYLPDVP EALVAFLGTA AVGAIWSGCG
QDYAPSGAAG RLAQLAPVVL VTADGYRYNG KEIDKAPDSA ELAGLLEELR AHIVVGDPSR
QPDRDIEVLA FDDVIAPRGS SQPGSAPEGE ADTDLPVRVP FDHPLWVLFS SGTTGRPKGI
VHGHGGVVVE HLKAAGLHAD LSHEDVFFWH TALSWMMWNF QAAGLLVGAE IVCYSGSPLY
PDADRLWALV ADERVTYFGT SPGQLQASRK AGLVPGRDHD LAMLRGIGST GSALSADLFE
WIDENVRPGI PVSSISGGTD VVTAFAGGSS GQPVVPGELS VRYLGVALAS WAPDATPLVD
EVGEMVVTAP MPSMPVSFWN DPGGERYRAA YFAHEWTGAT DTPVVWRHGD WVTVTDRGSL
VIHGRSDATL NKQGVRMGSA DIYEVVESLD EVAEAFVLGV DGPDGKYWMP LFVTLVPGAA
LDDRLRSTIA SSIRTRLSPR HIPDEVIEAP GIPHTRTGKK LEVPVTAILA GRTGVDVDPR
SIDDPGLIDW YAARGREHRW
//
