ID   L7KME8_9ACTN            Unreviewed;       383 AA.
AC   L7KME8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:GAC49681.1};
GN   Name=crtE {ECO:0000313|EMBL:GAC49681.1};
GN   ORFNames=GOACH_16_00630 {ECO:0000313|EMBL:GAC49681.1};
OS   Gordonia aichiensis NBRC 108223.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1220583 {ECO:0000313|EMBL:GAC49681.1, ECO:0000313|Proteomes:UP000010988};
RN   [1] {ECO:0000313|EMBL:GAC49681.1, ECO:0000313|Proteomes:UP000010988}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108223 {ECO:0000313|EMBL:GAC49681.1,
RC   ECO:0000313|Proteomes:UP000010988};
RA   Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA   Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia aichiensis NBRC 108223.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC49681.1}.
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DR   EMBL; BANR01000016; GAC49681.1; -; Genomic_DNA.
DR   RefSeq; WP_005176276.1; NZ_BANR01000016.1.
DR   AlphaFoldDB; L7KME8; -.
DR   STRING; 1220583.GOACH_16_00630; -.
DR   eggNOG; COG0142; Bacteria.
DR   OrthoDB; 4497239at2; -.
DR   Proteomes; UP000010988; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   CDD; cd00685; Trans_IPPS_HT; 1.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR   PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010988};
KW   Transferase {ECO:0000256|RuleBase:RU004466}.
SQ   SEQUENCE   383 AA;  39850 MW;  3C72A6F68018094C CRC64;
     MTSTVPVPTR LPEVPGAVES VLREFLDTAV STAAGISPVV GSSAQVVADF VLSGGKRIRP
     VFAFAGWQAG LSDPARVPTG STDSDALRVC AALELVQGCA LIHDDIIDAS DTRRGRPTVH
     RVFERGHRES GWRGDAAAHG VASAILAGDF ALAWADDLVH GYVPATLTPA GRPAGHADVR
     PLPPAAIATW AAMRTEVLGG QVLDIVNEVS GEESADAAYR VMEFKTAAYT VARPLELGAR
     VAGASDGLID QLRSVGHDLG IAFQLQDDLL GVFGDPERTG KPSGDDLAAG KRTALLALGL
     SRADDRDPAL GDALRSVVGT ELSADDLATA RGILTDVGAV ADIERTIDTL LDSAVTTLES
     TDIDDAVYTD LVAVARRMAH RDA
//