ID   L7KRE9_9ACTN            Unreviewed;       294 AA.
AC   L7KRE9;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Acetaldehyde dehydrogenase CmtH {ECO:0000313|EMBL:GAC51076.1};
DE   Flags: Fragment;
GN   Name=cmtH {ECO:0000313|EMBL:GAC51076.1};
GN   ORFNames=GOACH_41_00100 {ECO:0000313|EMBL:GAC51076.1};
OS   Gordonia aichiensis NBRC 108223.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1220583 {ECO:0000313|EMBL:GAC51076.1, ECO:0000313|Proteomes:UP000010988};
RN   [1] {ECO:0000313|EMBL:GAC51076.1, ECO:0000313|Proteomes:UP000010988}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108223 {ECO:0000313|EMBL:GAC51076.1,
RC   ECO:0000313|Proteomes:UP000010988};
RA   Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA   Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia aichiensis NBRC 108223.";
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the acetaldehyde dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00009244}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC51076.1}.
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DR   EMBL; BANR01000041; GAC51076.1; -; Genomic_DNA.
DR   RefSeq; WP_005180105.1; NZ_BANR01000041.1.
DR   AlphaFoldDB; L7KRE9; -.
DR   STRING; 1220583.GOACH_41_00100; -.
DR   eggNOG; COG4569; Bacteria.
DR   OrthoDB; 9786743at2; -.
DR   Proteomes; UP000010988; Unassembled WGS sequence.
DR   GO; GO:0008774; F:acetaldehyde dehydrogenase (acetylating) activity; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   HAMAP; MF_01657; Ac_ald_DH_ac; 1.
DR   InterPro; IPR003361; Acetaldehyde_dehydrogenase.
DR   InterPro; IPR015426; Acetylaldehyde_DH_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   NCBIfam; TIGR03215; ac_ald_DH_ac; 1.
DR   Pfam; PF09290; AcetDehyd-dimer; 1.
DR   Pfam; PF01118; Semialdhyde_dh; 1.
DR   PIRSF; PIRSF015689; Actaldh_dh_actl; 1.
DR   SMART; SM00859; Semialdhyde_dh; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010988}.
FT   DOMAIN          4..120
FT                   /note="Semialdehyde dehydrogenase NAD-binding"
FT                   /evidence="ECO:0000259|SMART:SM00859"
FT   NON_TER         294
FT                   /evidence="ECO:0000313|EMBL:GAC51076.1"
SQ   SEQUENCE   294 AA;  30903 MW;  211D7BE1BC94CD28 CRC64;
     MTTKVAVIGS GNIGTDLVIK IKRLARNLEI AVLVGIDPAS EGLARARRLG VDTVDNGVRG
     LVEHPAFDDI SIIFDATSAD AHRVNVEVLK PYGKRLIDLT PAALGPFVVP PVNLDEHLDA
     QIVNMVTCGG QATIPIVAAI GAVTTVHYAE IVASIASKSA GPGTRANIDE FTETTARAIE
     VVGGAAHGKA IIVLNPADPP LIMRDTVLAL VTSPDQEAIR ASVRGMAVRV AEYVPGYRLK
     QQVQFARLDP SDSIATLTSG QPVGADLWKV TVFLEVEGAA HYLPAYAGNL DIRG
//