ID L7LCW9_9ACTN Unreviewed; 501 AA.
AC L7LCW9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Aldehyde dehydrogenase {ECO:0000256|PIRNR:PIRNR036492};
GN ORFNames=GOHSU_27_00580 {ECO:0000313|EMBL:GAC57922.1};
OS Gordonia hirsuta DSM 44140 = NBRC 16056.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1121927 {ECO:0000313|EMBL:GAC57922.1, ECO:0000313|Proteomes:UP000053405};
RN [1] {ECO:0000313|EMBL:GAC57922.1, ECO:0000313|Proteomes:UP000053405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 16056 {ECO:0000313|EMBL:GAC57922.1,
RC ECO:0000313|Proteomes:UP000053405};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Katsumata H., Baba S.,
RA Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia hirsuta NBRC 16056.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|PIRNR:PIRNR036492,
CC ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC57922.1}.
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DR EMBL; BANT01000027; GAC57922.1; -; Genomic_DNA.
DR RefSeq; WP_005941012.1; NZ_BANT01000027.1.
DR AlphaFoldDB; L7LCW9; -.
DR STRING; 1121927.GOHSU_27_00580; -.
DR eggNOG; COG1012; Bacteria.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000053405; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR PIRSF; PIRSF036492; ALDH; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|PIRNR:PIRNR036492};
KW Reference proteome {ECO:0000313|Proteomes:UP000053405}.
FT DOMAIN 41..456
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 229
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1,
FT ECO:0000256|PROSITE-ProRule:PRU10007"
FT ACT_SITE 263
FT /evidence="ECO:0000256|PIRSR:PIRSR036492-1"
SQ SEQUENCE 501 AA; 54518 MW; 2FDCE8EABA47D33B CRC64;
MTKPAEVSVR AGDKVSSESH SLSELLEIQK AAFLRDGIPD AKTRIDRINR LGQLLLDNED
AISEALAADF GTRPRELSVA TDVAGCLIDL THQRRHAAEW MKTTNVSKIQ GLLGFKQRLR
HDPLGVVGIM GPWNFPLQLT FVPAGSAFAA GNRVLMRPSS VTRRTTEVIA RLAPDYFSIE
ELAVVTSAHG GGAEFAKLPV DHMFFTGSPE VGSSVAQEAA KNLVPVTLEL GGKNPAIVDL
DTDITEAANF LADARMINGG QVCLCPDYVF VPESKVGEFT DKVMARWTKN FPTIVDNGQY
TSTINEKNYT RIVGLIDDAV SLGATKHQVI PAGETLPNAA ERKIPPTLLT GVKAGMKIEE
DEVFGPVLTV YPYRNQSEAI DKINSAGHPL TLYWVGKDNE RLEFVAEHTR SGSISGNDFA
LHLLSGGLPF GGVGRSGMGN YHGRYGFETF SHARAVTVSS MPIKFAELVS APFTKSDVRM
TNMQMKMWKF LNGRASRKSA R
//
