ID L7LJI3_9ACTN Unreviewed; 930 AA.
AC L7LJI3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Putative acetate--CoA ligase {ECO:0000313|EMBL:GAC60896.1};
GN ORFNames=GSI01S_13_00790 {ECO:0000313|EMBL:GAC60896.1};
OS Gordonia sihwensis NBRC 108236.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1223544 {ECO:0000313|EMBL:GAC60896.1, ECO:0000313|Proteomes:UP000035083};
RN [1] {ECO:0000313|EMBL:GAC60896.1, ECO:0000313|Proteomes:UP000035083}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108236 {ECO:0000313|EMBL:GAC60896.1,
RC ECO:0000313|Proteomes:UP000035083};
RA Yoshida I., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia sihwensis NBRC 108236.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC60896.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BANU01000013; GAC60896.1; -; Genomic_DNA.
DR AlphaFoldDB; L7LJI3; -.
DR eggNOG; COG1042; Bacteria.
DR eggNOG; COG1670; Bacteria.
DR Proteomes; UP000035083; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Ligase {ECO:0000313|EMBL:GAC60896.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000035083}.
FT DOMAIN 46..202
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 721..757
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 930 AA; 98547 MW; 79792C3BE7A33B9E CRC64;
MTDTPDTGST DTASDTEDTP TTEDALPREY PRQWSADVLA SDGGVVHIRP IMPADADLLV
EFHNGLSERT RYMRYFGPTP TLPPREVVRM TTVDYRNRVA LLAFLGDRVI AMGLYEGLAA
DGKPTSAEVA FVVADDHQGR GLGPILLEHL AGAAAENGFT RFEAEVLSEN PNMVAVFRDA
GYQISRAFDG STVHVEFLID PTEALTAVRN ARERASEARS IANLLRPSSV AVIGASADPK
KVGNVLLANV LAAGFTGPVF PVNGSAVASE PDDAQPRRGP GRPPRTAPPS VRGIRSYSTV
RDIPDPVDLA VIAVPAARID QVLDDCLAKG VRTLVVVSAG FGEKGEAGLE NEKRLAEQVR
AHGMRLVGPN ALGVVNNHPD IALNASLAPR IPGAGRVGFF CQSGALGIAI LDTAAHRRLG
LSTFVSAGNR ADVSGNDVLQ YWDTDDDTDV VLLYLESFGN PRKFGRIARR VASKKPIVAI
KSGSGAMSPV HAQRTGPVRD DRVAQMVLEQ AGVIQVETIA ELFDSATVLA YQPLPDGPRT
AILGNSSVIA SLAANTARSS GLEVVSIVDL GPAVTHDALS AAVAEAMNDD AIDAVIVVFV
PPVAVDSSDY ALGLLEATRP ADGGDVPTKP VVTTFLAVEG VPPGLSRTGP DGLPVRGSIP
SYPTPERAAS ALAQAWRYSR WRSRPAAAPA PIPDSRPEDA RSFVREAMAD GPRSLTPREG
SYVLGHFGIE VVPFRDVRTM HEASAAAREL GFPVVVKSTS PAWVGRVDRE GARLDLSDAT
AVITAFNELQ TLTGDSSLQV QRMAPKGVGM YLRVSDSPSF GPLMSFGLSG RLFEALGDRS
FRSIPLTEHD ARELVDEPSV RTLLAEDHTD PDALVELLQR VSALIDDVPE IRELTLDPIL
ASPDGISVLG SHIDVGPVPT LADTGPRRLG
//
