ID   L7MZQ8_ANOCA            Unreviewed;       539 AA.
AC   L7MZQ8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   29-SEP-2021, sequence version 2.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377 {ECO:0000313|Ensembl:ENSACAP00000007384.3, ECO:0000313|Proteomes:UP000001646};
RN   [1] {ECO:0000313|Ensembl:ENSACAP00000007384.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JBL SC #1 {ECO:0000313|Ensembl:ENSACAP00000007384.3};
RG   The Genome Sequencing Platform;
RA   Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J.,
RA   Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Anolis carolinensis (Green Anole Lizard).";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSACAP00000007384.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   AlphaFoldDB; L7MZQ8; -.
DR   STRING; 28377.ENSACAP00000007384; -.
DR   ESTHER; anoca-l7mzq8; Carb_B_Chordata.
DR   Ensembl; ENSACAT00000007540.3; ENSACAP00000007384.3; ENSACAG00000007244.3.
DR   eggNOG; KOG1516; Eukaryota.
DR   GeneTree; ENSGT00940000155200; -.
DR   HOGENOM; CLU_006586_13_0_1; -.
DR   Proteomes; UP000001646; Unplaced.
DR   Bgee; ENSACAG00000007244; Expressed in kidney and 6 other cell types or tissues.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd00312; Esterase_lipase; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF416; CARBOXYLESTERASE 3; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001646}.
FT   DOMAIN          6..517
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   539 AA;  59220 MW;  29329CA49FFD471C CRC64;
     PHGVRPTVST RLGRLRGTLL SVEGAPAPVK AFLGVPFAKP PLGTLRFAPP EPPEPWSHLR
     DATSQPPMCL QDVSWMQVMA HALNIVPPNV SASEDCLYLN VFTPDTEAKL PVLVSIHGGG
     LIAGSASMYD TPALSAFENV VLVVLQYRLG IPGFFSTGSK EAPGNWGLLD QVAALRWVQE
     NIEAFGGDPT SVTIMGESAG GFSVGVQVLS PLSRGLFHRA ISESGVALLN ILAVKDLRAM
     VQTVANVSGC ENSSPAALVR CLRSKTEEEL AALNIQLCQV FGSALAVVDG KLLPKAPEEL
     LAAKEFRKVP YLIGINNHEY GWTLPQSGLF VSITEVMDRQ AVTAAFQESA PVLNIPVEAT
     QRALKEYVGE TEDPRELRAQ FLDYMGDVMF LLPSVRTARA HRDSGAPVYF YQFQHRPSIF
     RDTRPVYVKA DHVDQVIFVS GTPLLRSKDS PLGEYTEEEK RLSKTMMRYW ANFARSGNPN
     GRGQVKWPRY DQKEGYLELG LEPRGAQKLK QDKVDFWLKT LPEQMREETA RGKDTPRAV
//