ID L7N3T2_XENTR Unreviewed; 310 AA.
AC L7N3T2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=C1q and TNF related 3 {ECO:0000313|Ensembl:ENSXETP00000045602};
DE SubName: Full=Complement C1q tumor necrosis factor-related protein 3 isoform X1 {ECO:0000313|RefSeq:XP_017946506.1};
GN Name=c1qtnf3 {ECO:0000313|Ensembl:ENSXETP00000045602,
GN ECO:0000313|RefSeq:XP_017946506.1,
GN ECO:0000313|Xenbase:XB-GENE-962278};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000045602};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000045602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000045602};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000045602}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2013) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_017946506.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_017946506.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_017946506.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_017946506.1; XM_018091017.2.
DR Ensembl; ENSXETT00000045602; ENSXETP00000045602; ENSXETG00000030739.
DR GeneID; 100490044; -.
DR KEGG; xtr:100490044; -.
DR CTD; 114899; -.
DR Xenbase; XB-GENE-962278; c1qtnf3.
DR eggNOG; ENOG502QSK2; Eukaryota.
DR HOGENOM; CLU_001074_0_1_1; -.
DR OMA; KVAFMAS; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Bgee; ENSXETG00000030739; Expressed in skeletal muscle tissue and 1 other cell type or tissue.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427:SF49; C1Q DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR PRINTS; PR00007; COMPLEMNTC1Q.
DR SMART; SM00110; C1Q; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..310
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041198343"
FT DOMAIN 177..310
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 114..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 34243 MW; 8BECC6313BB0DBA2 CRC64;
MASTRLSIWW LLALLTLPFC LCQDEHMEVR RRFNKPVARV VESRHQRTSN NAPSREVVGQ
LDQLVEAFAN NSSADTVLMR QEVDDLEQPS HRVQTPQQPE CNCCRGDFGY RLHQPVSGPP
GLPGPPGLPG NHGNNGNNGA TGQEGAKGEK GDKGDMGPRG ERGHIGVKGE KGHPGVPPEL
QVAFMASMAT HFSNINSGII FSSVETNVGN FFDVMTGRFS APVTGIYFFT FHMLKHEEVE
DVYVYLMHNG NTIVSMYSYE TKGKQDTSGN SAVLKLAKED EVWLRMGTGA LHGDHQRYCT
FCGFLLFETK
//
